| 9671782 |
Ming D, Ruiz-Avila L, Margolskee RF: Characterization and solubilization of bitter-responsive receptors that couple to gustducin. Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8933-8.
In this paper, we show that gustducin is expressed in bovine taste tissue and that both gustducin and transducin, in the presence of bovine taste membranes, can be activated specifically by several bitter compounds, including denatonium, quinine, and strychnine.
The taste receptor-gustducin interaction can be competitively inhibited by peptides derived from the sites of interaction of rhodopsin and transducin. |
1(0,0,0,1) |
Details |