| Name | mGluR1 |
|---|---|
| Synonyms | GPRC1A; GRM 1; GRM1; GRM1 alpha; GRM1A; MGLUR 1; MGLUR1; MGLUR1A… |
| Name | strychnine |
|---|---|
| CAS | strychnidin-10-one |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 11139828 | Tranquillini ME, Reggiani A: -site antagonists and stroke. . Expert Opin Investig Drugs. 1999 Nov;8(11):1837-1848. Its action is mediated by two main groups of receptors: the ionotropic receptors (which include AMPA and kainic acid subtypes) and the metabotropic receptors (mGluR (1-8)) mediating G-protein coupled responses. This review focuses on the strychnine insensitive binding site located on the NMDA receptor channel, and on the possible use of selective antagonists for the treatment of stroke. |
1(0,0,0,1) | Details |
| 19321640 | Bonnot A, Chub N, Pujala A, O'Donovan MJ: Excitatory actions of ventral root stimulation during network activity generated by the disinhibited neonatal mouse spinal cord. J Neurophysiol. 2009 Jun;101(6):2995-3011. Epub 2009 Mar 25. Bath application of the type I mGluR1 receptor antagonist CPCCOEt reduced the ability of both dorsal root and VR stimulation to entrain the disinhibited rhythm and abolished the ability of either type of stimulation to evoke locomotor-like activity. |
1(0,0,0,1) | Details |