Protein Information

Name P15
Synonyms HRES 1; P25; p15; P15 protein; HRES1; HTLV 1 related endogenous sequence; HTLV related endogenous sequence 1; P25 protein…

Compound Information

Name strychnine
CAS strychnidin-10-one

Reference List

PubMed Abstract RScore(About this table)
11956334 Zhang W, Barnbrock A, Gajic S, Pfeiffer A, Ritter B: Differential ontogeny of GABA (B)-receptor-mediated pre- and postsynaptic modulation of GABA and glycine transmission in respiratory rhythm-generating network in mouse. J Physiol. 2002 Apr 15;540(Pt 2):435-46.

Using brainstem slices of neonatal mice (postnatal day, P0-P15), we analysed the role of GABA (B)-mediated modulation of GABA and glycine synaptic transmission in the respiratory network.
The effect of CGP on respiratory frequency was diminished in the presence of bicuculline and strychnine in older but not in younger animals.
3(0,0,0,3) Details
17656439 Mitchell EA, Gentet LJ, Dempster J, Belelli D: GABAA and glycine receptor-mediated transmission in rat lamina II neurones: relevance to the analgesic actions of neuroactive steroids. J Physiol. 2007 Sep 15;583(Pt 3):1021-40. Epub 2007 Jul 26.

In this study, we have compared the actions of 5alpha3alpha and minaxolone upon inhibitory transmission mediated by both GABA (A) and strychnine-sensitive GlyRs in lamina II neurones of juvenile (P15-21) rats.
31(0,1,1,1) Details
15728841 Gonzalez-Forero D, Alvarez FJ: Differential postnatal maturation of GABAA, glycine receptor, and mixed synaptic currents in Renshaw cells and ventral spinal interneurons. J Neurosci. 2005 Feb 23;25(8):2010-23.


Thus, we analyzed glycinergic and GABAergic "inhibitory" miniature postsynaptic currents (mPSCs) in neonatal [postnatal day 1 (P1) to P5] and mature (P9-P15) RCs and compared them to other ventral interneurons (non-RCs).
3(0,0,0,3) Details
19720114 Cooke JE, Mathers DA, Puil E: Isovaline causes inhibition by increasing potassium conductance in thalamic neurons. Neuroscience. 2009 Dec 15;164(3):1235-43. Epub 2009 Aug 28.

In this paper, we examined the possibility that isovaline inhibits neurons by activating strychnine (Str)-sensitive glycine (A) receptors in ventrobasal thalamus.
Sagittal brain sections containing ventrobasal nuclei were prepared from P10-P15 rats.
1(0,0,0,1) Details