| 7650761 |
Aprison MH, Galvez-Ruano E, Lipkowitz KB: On a molecular comparison of strong and weak antagonists at the glycinergic receptor. J Neurosci Res. 1995 Jun 1;41(2):259-69.
Using molecular modeling techniques, we studied nine glycine antagonists in order to try to identify the molecular descriptors that characterize strychnine as a strong antagonist and N,N-dimethyl-muscimol, iso-THIA, THIA, N-methyl-THIP, iso-THAZ, THAZ, iso-THPO, and iso-THAO (see Experimental for chemical names) as weak glycine antagonists. |
81(1,1,1,1) |
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