Protein Information

Name T12
Synonyms CD6; CD6 antigen; CD6 molecule; T cell differentiation antigen CD6; T cell differentiation antigen CD6 precursor; T12; TP120; CD6 antigens…

Compound Information

Name strychnine
CAS strychnidin-10-one

Reference List

PubMed Abstract RScore(About this table)
9084588 Kremer E, Lev-Tov A: Localization of the spinal network associated with generation of hindlimb locomotion in the neonatal rat and organization of its transverse coupling system. J Neurophysiol. 1997 Mar;77(3):1155-70.

An alternating rhythm persisted also in preparations that were midsagittally split up to T13-T12, or down to L4.
Bath application of the glycine receptor antagonist strychnine, or the gamma-aminobutyric acid-A (GABAA) receptor blocker bicuculline, induced in the presence of NMDA and 5-HT a bilaterally synchronous rhythm in any intact or detached segment of the cord and in midsagittally split preparations with few bilaterally intact upper thoracic or lower sacral segments.
2(0,0,0,2) Details
7897483 Wall PD, Bennett DL: Postsynaptic effects of long-range afferents in distant segments caudal to their entry point in rat spinal cord under the influence of picrotoxin or strychnine. J Neurophysiol. 1994 Dec;72(6):2703-13.

On one side dorsal roots T12, T13, and L1 were intact but all more caudal roots on that side were cut.
1(0,0,0,1) Details
8816361 del Carmen Garcia M, Enero MA, Celuch SM: Hypotensive and hypertensive effects of catecholamines intrathecally injected in anesthetized rats. J Auton Nerv Syst. 1996 Jun 10;59(1-2):17-26.

The glycine-receptor antagonist strychnine (25 micrograms, i.t.) did not modify the hypotension induced by either noradrenaline (in the presence of prazosin) or adrenaline.
The cardiovascular effects of catecholamines intrathecally (i.t.) injected at the T12-L1 level were analyzed in pentobarbital anesthetized rats.
1(0,0,0,1) Details