Protein Information

Name adenylate cyclase
Synonyms AH related protein; HCA2; ATP pyrophosphate lyase; Adenylate cyclase; Adenylyl cyclase soluble; HCA 2; RP1 313L4.2; SAC…

Compound Information

Name strychnine
CAS strychnidin-10-one

Reference List

PubMed Abstract RScore(About this table)
16018586 Salceda R, Aguirre-Ramirez M: Characterization of strychnine-sensitive glycine receptor in the intact frog retina: modulation by protein kinases. Neurochem Res. 2005 Mar;30(3):411-6.

Binding of both radioligands was considerably reduced by compounds that inhibit or activate adenylate cyclase and increased cAMP levels.
1(0,0,0,1) Details
8714523 Puebla L, Arilla E: Glycine increases the number of somatostatin receptors and somatostatin-mediated inhibition of the adenylate cyclase system in the rat hippocampus. J Neurosci Res. 1996 Feb 1;43(3):346-54.

This effect seems to be mediated by inhibitory strychnine-sensitive glycine receptors since pretreatment with the antagonist strychnine (80 micrograms/100 g body weight, intravenously) abolished this response.
1(0,0,0,1) Details