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Liu T, Fujita T, Nakatsuka T, Kumamoto E: Phospholipase A2 activation enhances inhibitory synaptic transmission in rat substantia gelatinosa neurons. J Neurophysiol. 2008 Mar;99(3):1274-84. Epub 2008 Jan 23.
The former action is mediated by glutamate-receptor activation and neuronal activity increase, possibly the facilitatory effect of PLA (2) activation on excitatory transmission, whereas the latter action is due to PLA (2) and subsequent lipoxygenase activation and is independent of extracellular Ca (2+). |
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