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Liu Z, Ramanoudjame G, Liu D, Fox RO, Jayaraman V, Kurnikova M, Cascio M: Overexpression and functional characterization of the extracellular domain of the human alpha1 glycine receptor. Biochemistry. 2008 Sep 16;47(37):9803-10. Epub 2008 Aug 19.
The mutant GlyR ECD, named GlyBP, was present in both soluble and membrane-associated fractions after cell lysis, though only the latter appeared to be in a native-like conformation capable of binding strychnine, a GlyR specific antagonist. |
34(0,1,1,4) |
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