| Name | alpha 2 adrenergic receptors (protein family or complex) |
|---|---|
| Synonyms | Alpha adrenoceptor; Alpha adrenoceptor; Alpha adrenergic receptor; Alpha adrenergic receptors; Alpha adrenoceptors; Alpha adrenoceptors; alpha1 Adrenoceptors; alpha1 Adrenoceptor… |
| Name | strychnine |
|---|---|
| CAS | strychnidin-10-one |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9181635 | Riekkinen M, Kemppainen S, Riekkinen P Jr: Effects of stimulation of alpha 1-adrenergic and /-B receptors on learning defects in aged rats. Psychopharmacology. 1997 May;131(1):49-56. The present study was designed to investigate the efficacy of stimulation of alpha1-adrenoceptors and the strychnine insensitive -B binding sites of the (NMDA) receptor complex to alleviate the age-related defect in water maze (WM) spatial (hidden platform) navigation. |
32(0,1,1,2) | Details |
| 11929913 | Pan YZ, Li DP, Pan HL: Inhibition of glutamatergic synaptic input to spinal lamina II (o) neurons by presynaptic alpha (2)-adrenergic receptors. J Neurophysiol. 2002 Apr;87(4):1938-47. The miniature excitatory postsynaptic currents (mEPSCs) were recorded in the presence of tetrodotoxin, bicuculline, and strychnine. |
4(0,0,0,4) | Details |
| 10051215 | Nabekura J, Xu TL, Rhee JS, Li JS, Akaike N: Alpha2-adrenoceptor-mediated enhancement of response in rat sacral dorsal commissural neurons. Neuroscience. 1999 Mar;89(1):29-41. In addition, potentiated the strychnine-sensitive postsynaptic currents evoked in a slice preparation of sacral dorsal commissural nucleus. |
2(0,0,0,2) | Details |
| 8594938 | Li YW, Bayliss DA, Guyenet PG: C1 neurons of neonatal rats: intrinsic beating properties and alpha 2-adrenergic receptors. Am J Physiol. 1995 Dec;269(6 Pt 2):R1356-69. Blockade of fast postsynaptic potentials with plus bicuculline plus strychnine or with a low-Ca (2+)-high-Mg2+ medium failed to reduce their firing rate. |
2(0,0,0,2) | Details |
| 9593880 | Miyazaki T, Kobayashi H, Tosaka T: Presynaptic inhibition by of the EPSC evoked in neonatal rat sympathetic preganglionic neurons. Brain Res. 1998 Apr 20;790(1-2):170-7. Monosynaptic excitatory postsynaptic currents (EPSCs) were evoked by electrical stimulation of the nucleus intercalatus in the presence of strychnine (5 microM) and bicuculline (10 microM). A comparable degree of EPSC depression was also seen with the alpha2-adrenoceptor agonist clonidine (5 microM), and the alpha2A-agonist oxymetazoline (5 microM), while the alpha1-agonist (100 microM) caused only a 22% depression. |
1(0,0,0,1) | Details |
| 10669492 | Hayar A, Guyenet PG: Prototypical imidazoline-1 receptor ligand moxonidine activates alpha2-adrenoceptors in bulbospinal neurons of the RVL. J Neurophysiol. 2000 Feb;83(2):766-76. Excitatory postsynaptic currents (EPSCs) evoked by focal electrical stimulation were isolated by incubation with gabazine and strychnine, and inhibitory postsynaptic currents (IPSCs) were isolated with 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX). Prazosin was used to block alpha1-adrenoceptors. |
1(0,0,0,1) | Details |
| 8735788 | Streit J: Mechanisms of pattern generation in co-cultures of embryonic spinal cord and skeletal muscle. Int J Dev Neurosci. 1996 Apr;14(2):137-48. These neuron-driven activity patterns changed from random to rhythmic when the inhibitory synapses in the spinal cord were blocked by strychnine, bicuculline or both. Such patterns were, however, modulated through muscarinic and alpha-adrenergic receptors. |
1(0,0,0,1) | Details |
| 10604951 | Snell LD, Claffey DJ, Ruth JA, Valenzuela CF, Cardoso R, Wang Z, Levinson SR, Sather WA, Williamson AV, Ingersoll NC, Ovchinnikova L, Bhave SV, Hoffman PL, Tabakoff B: Novel structure having antagonist actions at both the site of the N-methyl-D-aspartate receptor and neuronal voltage-sensitive channels: biochemical, electrophysiological, and behavioral characterization. J Pharmacol Exp Ther. 2000 Jan;292(1):215-27. These compounds were shown to act in a use-dependent manner as antagonists of VSNaCs and to act as selective competitive antagonists at the strychnine-insensitive recognition site of NMDA receptors. |
0(0,0,0,0) | Details |
| 9671104 | Garcia MC, Celuch SM, Adler-Graschinsky E: Involvement of and glutamate receptors in the blood pressure responses to intrathecally injected sodium nitroprusside in anesthetized rats. Eur J Pharmacol. 1998 May 22;349(2-3):245-52. The blood pressure responses to sodium nitroprusside were not modified by blockade of muscarinic receptors with methyl atropine (164 nmol, i.t.), or of nicotinic receptors with hexamethonium (211 nmol, i.t.), of alpha1-adrenoceptors with prazosin (3.1 nmol, i.t.), of alpha2-adrenoceptors with yohimbine (2.8 micromol/kg, i.v.), of receptors with methysergide (5.1 micromol/kg, i.v.), or of glycine receptors with strychnine (65 nmol, i.t.). |
0(0,0,0,0) | Details |