| Name | neurokinin 1 receptor |
|---|---|
| Synonyms | NK 1 receptor; NK 1R; NK1R; NKIR; Neurokinin 1 receptor; SPR; Substance P Receptor; TAC1R… |
| Name | strychnine |
|---|---|
| CAS | strychnidin-10-one |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16467532 | Torsney C, MacDermott AB: Disinhibition opens the gate to pathological pain signaling in superficial neurokinin 1 receptor-expressing neurons in rat spinal cord. J Neurosci. 2006 Feb 8;26(6):1833-43. Blockade of local GABAergic and glycinergic inhibition with bicuculline (10 microm) and strychnine (300 nm), respectively, revealed significant A fiber input to lamina I NK1R+ neurons that was predominantly Abeta fiber mediated. |
38(0,1,1,8) | Details |
| 12144849 | Chitravanshi VC, Sapru HN: Microinjections of into the pre-Botzinger complex inhibit phrenic nerve activity in the rat. Brain Res. 2002 Aug 23;947(1):25-33. Neurokinin-1 receptor immunoreactivity in the semi-compact region of the nucleus ambiguus and the area immediately ventral to it indicated that the site of microinjections was in the general region of pre-Botzinger complex. The effects of were prevented by a prior microinjection of strychnine (0.5 mM) into the pre-Botzinger complex. |
1(0,0,0,1) | Details |
| 19244526 | Miraucourt LS, Moisset X, Dallel R, Voisin DL: inhibitory dysfunction induces a selectively dynamic, morphine-resistant, and neurokinin 1 receptor- independent mechanical allodynia. J Neurosci. 2009 Feb 25;29(8):2519-27. First, we showed that disinhibition with strychnine selectively induced dynamic but not static mechanical allodynia. |
1(0,0,0,1) | Details |
| 7684071 | Calligaro DO, O'Malley PJ, Monn JA: beta-Amyloid (25-35) or substance P stimulates [3H] MK-801 binding to rat cortical membranes in the presence of and J Neurochem. 1993 Jun;60(6):2297-303. The compounds do not appear to act through the strychnine-insensitive binding site because neither beta-amyloid (25-35) nor substance P displaced [3H] binding. |
0(0,0,0,0) | Details |