| Name | brains |
|---|---|
| Synonyms | BPG dependent PGAM 1; Brain; CDABP0006; PGAM 1; PGAM B; PGAM1; PGAM1 protein; PGAMA… |
| Name | strychnine |
|---|---|
| CAS | strychnidin-10-one |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10890022 | Nishikawa T, Yamamoto N, Tsuchida H, Umino A, Kawaguchi N: [Endogenous in mammalian brains] . Nihon Shinkei Seishin Yakurigaku Zasshi. 2000 Feb;20(1):33-9. It is well established that, like and D- potentiates neurotransmission via the (NMDA) receptor by selective stimulation of its strychnine-insensitive site and acts as a co-agonist of the glutamate receptor. |
2(0,0,0,2) | Details |
| 12769957 | Pichon Y, Guillet JC, Le Guen J, Tiaho F, Van Eyseren I: Effects of nicotinic and muscarinic ligands on embryonic neurones of Periplaneta americana in primary culture: a whole cell clamp study. J Insect Physiol. 1998 Mar;44(3-4):227-240. The pharmacological properties of receptors of cultured neurones from embryonic cockroach brains were studied using the whole-cell configuration of the patch-clamp technique. The sequence of decreasing potency of the antagonists of the response was: methyllycaconitine > alpha-bungarotoxin > mecamylamine > curare > strychnine > bicuculline > atropine > picrotoxin. |
1(0,0,0,1) | Details |
| 9792190 | Nagata Y, Uehara T, Kitamura Y, Nomura Y, Horiike K: content and D-[3H] serine binding in the brain regions of the senescence-accelerated mouse. Mech Ageing Dev. 1998 Aug 14;104(2):115-24. binds to strychnine-insensitive binding sites of the (NMDA) receptor complex, and enhances binding to the receptor complex. A receptor autoradiographical analysis showed that the D-[3H] serine binding to the brain section was highest in the hippocampus, and the binding in the SAMP8 brains was lower than that of the SAMR1. |
1(0,0,0,1) | Details |
| 9895138 | Toru M: Biological research on schizophrenia. . Psychiatry Clin Neurosci. 1998 Dec;52 Suppl:S170-2. Glutamate receptors, such as the kainate receptor labeled by 3H-kainate, the (NMDA) receptor by 3H MK801, and the strychnine-insensitive sites in the NMDA receptor by 3H- increased significantly in various cortical areas of schizophrenic brains. |
32(0,1,1,2) | Details |
| 7909453 | Ishimaru M, Kurumaji A, Toru M: Increases in strychnine-insensitive binding sites in cerebral cortex of chronic schizophrenics: evidence for hypothesis. Biol Psychiatry. 1994 Jan 15;35(2):84-95. Strychnine-insensitive binding sites, an absolute requirement of the responses mediated by (NMDA) receptors, were measured in the postmortem brains of 13 chronic schizophrenics and 10 controls, using a radiolabeled receptor assay. |
31(0,1,1,1) | Details |
| 7537613 | Musshoff U, Madeja M, Bloms-Funke P, Speckmann EJ: Effects of the epileptogenic agent strychnine on membrane currents elicited by agonists of the and non-NMDA receptors in Xenopus oocytes. Comp Biochem Physiol A Physiol. 1995 May;111(1):65-71. The effects of strychnine (STRY) on ion channels activated by kainate (KA), alpha-amino-3--5-methyl-4-isoxazolpropionate (AMPA) and quisqualate (QUIS) were studied using Xenopus oocytes, microinjected with mRNA from rats' brains. |
31(0,1,1,1) | Details |
| 8836221 | Kumamoto E, Murata Y: current in rat septal cholinergic neuron in culture: monophasic positive modulation by Zn2+. J Neurophysiol. 1996 Jul;76(1):227-41. Membrane currents induced by (Iglys) were investigated in cholinergic neurons in primary culture, isolated from the septal region of fetal rat brains, by use of the whole cell voltage-clamp recording configuration. Strychnine inhibited Igly in a dose-dependent and competitive manner; it took at most 1 min for this action to be attained to a steady level. |
1(0,0,0,1) | Details |
| 9202334 | Matoba M, Tomita U, Nishikawa T: Characterization of 5,7-dichlorokynurenate-insensitive D-[3H] serine binding to synaptosomal fraction isolated from rat brain tissues. J Neurochem. 1997 Jul;69(1):399-405. Strychnine and 7-chlorokynurenate failed to inhibit the binding at 10 microM. The present findings indicate that the DCK-insensitive D-[3H] serine binding site could be a novel candidate for a target for endogenous in mammalian brains. |
1(0,0,0,1) | Details |
| 7823028 | Jursky F, Tamura S, Tamura A, Mandiyan S, Nelson H, Nelson N: Structure, function and brain localization of neurotransmitter transporters. J Exp Biol. 1994 Nov;196:283-95. A correlation as observed between the pattern we obtained and that observed previously from strychnine binding studies. We studied four different cDNAs encoding transporters and three different cDNAs encoding transporters in mouse and rat brains. |
1(0,0,0,1) | Details |
| 11152388 | Squires RF, Saederup E: Additivities of compounds that increase the numbers of high affinity [3H] muscimol binding sites by different amounts define more than 9 (A) receptor complexes in rat forebrain: implications for schizophrenia and clozapine research. Neurochem Res. 2000 Dec;25(12):1587-601. The binding of [3H] MUS alone, without enhancers may represent a ninth group of binding sites which is probably heterogeneous as indicated by the very low pseudo Hill coefficients for bicuculline and strychnine in displacing [3H] MUS without enhancer. |
0(0,0,0,0) | Details |