| Name | thyroid peroxidase |
|---|---|
| Synonyms | MSA; TPO; TPO protein; TPX; Thyroid microsomal antigen; Thyroid peroxidase; Thyroid peroxidase isoform d variant; Thyroid peroxidase precursor… |
| Name | hexachlorobenzene |
|---|---|
| CAS | 1,2,3,4,5,6-hexachlorobenzene |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18790515 | Langer P, Kocan A, Tajtakova M, Koska J, Radikova Z, Ksinantova L, Imrich R, Huckova M, Drobna B, Gasperikova D, Sebokova E, Klimes I: Increased thyroid volume, prevalence of thyroid antibodies and impaired fasting in young adults from organochlorine cocktail polluted area: outcome of transgenerational transmission?. Chemosphere. 2008 Oct;73(7):1145-50. Epub 2008 Sep 14. In 137 females (F) and 94 males (M) aged 21-35 years from organochlorines (OCs) polluted area (POLL) increased thyroid volume (ThV), prevalence of antibodies to thyroperoxidase (TPOab), thyrotropin receptor (TRab) and of impaired fasting (IFG) was found compared to 116 F and 107 M from background pollution area (BCGR). |
1(0,0,0,1) | Details |
| 18298316 | Radikova Z, Tajtakova M, Kocan A, Trnovec T, Sebokova E, Klimes I, Langer P: Possible effects of environmental nitrates and toxic organochlorines on human thyroid in highly polluted areas in Slovakia. Thyroid. 2008 Mar;18(3):353-62. In the area heavily polluted by an organochlorine (OC) cocktail consisting of polychlorinated biphenyls (PCBs), 2,2'-bis (4-chlorophenyl)-1,1-dichloroethylene (p,p'-DDE), hexachlorobenzene (HCB), and dioxins and furans (polluted area) and in the background pollution area (background area) a total of 2046 adults were examined. |
0(0,0,0,0) | Details |
| 17537484 | Langer P, Tajtakova M, Kocan A, Petrik J, Koska J, Ksinantova L, Radikova Z, Ukropec J, Imrich R, Huckova M, Chovancova J, Drobna B, Jursa S, Vlcek M, Bergman A, Athanasiadou M, Hovander L, Shishiba Y, Trnovec T, Sebokova E, Klimes I: Thyroid ultrasound volume, structure and function after long-term high exposure of large population to polychlorinated biphenyls, pesticides and dioxin. Chemosphere. 2007 Aug;69(1):118-27. Epub 2007 May 29. Serum levels of thyrotropin (TSH), thyroperoxidase antibodies (TPOab) and thyroglobulin were estimated by electrochemiluminiscent assay and these of 15 PCB congeners, p,p'-DDE, p,p'-DDT, hexachlorobenzene (HCB) and hexachlorocyclohexane by high-resolution gas chromatography. |
6(0,0,1,1) | Details |
| 17222442 | Langer P, Kocan A, Tajtakova M, Petrik J, Chovancova J, Drobna B, Jursa S, Radikova Z, Koska J, Ksinantova L, Huckova M, Imrich R, Wimmerova S, Gasperikova D, Shishiba Y, Trnovec T, Sebokova E, Klimes I: Fish from industrially polluted freshwater as the main source of organochlorinated pollutants and increased frequency of thyroid disorders and dysglycemia. Chemosphere. 2007 Apr;67(9):S379-85. Epub 2007 Jan 11. Recently, a total of 2045 adults from this and the surrounding background pollution area have been examined using questionnaire data, thyroid volume by ultrasound (ThV), urinary and serum levels of 15 PCB congeners, hexachlorobenzene (HCB), 2,2'-2-bis (4-chlorobiphenyl)-1,1-dichloroethylene (DDE), 2,2'-bis (4-chlorophenyl)-1,1,1-trichloroethane (DDT), alpha-, beta- and gamma-hexachlorocyclohexane (HCH), thyrotropin (TSH), free (FT4), anti-thyroperoxidase antibodies (TPOab) and fasting |
6(0,0,1,1) | Details |
| 18995849 | Schell LM, Gallo MV, Ravenscroft J, DeCaprio AP: Persistent organic pollutants and anti-thyroid peroxidase levels in Akwesasne Mohawk young adults. Environ Res. 2009 Jan;109(1):86-92. Epub 2008 Nov 7. Persistent organic pollutants, such as polychlorinated biphenyls (PCBs), hexachlorobenzene (HCB), and p,p'-dichlorophenyldichloroethylene (DDE), have been found to elicit a broad spectrum of biologic, metabolic, and immunologic responses. |
3(0,0,0,3) | Details |
| 19856712 | Cebecauer L, Radikova Z, Rovensky J, Koska, Imrich R, Ksinantova L, Susienkova K, Vigas M, Klimes I, Langer P: Increased prevalence and coincidence of antinuclear and antithyroid antibodies in the population exposed to high levels of polychlorinated pollutants cocktail. Endocr Regul. 2009 Apr;43(2):75-81. OBJECTIVES: Because of well known association between the exposure to persistent organochlorinated pollutants (POPs) and impaired immune system, it was attempted to check possible coincidence of nuclear and thyroperoxidase antibodies with the levels of major POPs. In the same cohort fifteen congeners of PCB and also total DDE (2,2'-bis (4-chlorophenyl)-1,1-dichloroethylene) and hexachlorobenzene (HCB) were estimated by high resolution gas chromatography/mass spectrometry. |
2(0,0,0,2) | Details |
| 8984768 | Langer P, Tajtakova M: [Organic chlorinated pollutants and the thyroid gland] . Vnitr Lek. 1996 Sep;42(9):615-9. This review presents the definition of main groups of organic chlorinated pollutants (polychlorinated biphenyls, dibenzodioxines, dibenzofurans, hexachlorobenzene, hexachlorocyclohexane, DDT etc.). In the employees of Chemko also significantly higher frequency of thyroid antibodies anti-thyroperoxidase, anti-thyroglobulin and anti-TST-receptor was found. |
1(0,0,0,1) | Details |
| 19335881 | Langer P, Kocan A, Tajtakova M, Susienkova K, Radikova Z, Koska J, Ksinantova L, Imrich R, Huckova M, Drobna B, Gasperikova D, Trnovec T, Klimes I: Multiple adverse thyroid and metabolic health signs in the population from the area heavily polluted by organochlorine cocktail (PCB, DDE, HCB, dioxin). Thyroid Res. 2009 Mar 31;2(1):3. METHODS: In a total of 2046 adults (834 males and 1212 females; age range 21-75) from POLL and BCGR the serum level of major POPs such as of 15 most abundant PCBs congeners, dichlorodiphenyl-dichloroethylene (p,p'-DDE) and hexachlorobenzene (HCB) was estimated by high resolution gas chromatography. In addition, the data on thyroid volume by ultrasound and body mass index were obtained and serum level of thyroperoxidase and thyrotropin receptor antibodies as well as that of free total thyrotropin, thyroglobulin, fasting and insulin, and triglycerides was measured. |
1(0,0,0,1) | Details |