Protein Information

Name ATPase
Synonyms ATP7A; MK; ATPase; Cation transporting ATPase; ATP7A protein; ATPase Cu(2+) transporting alpha polypeptide; Copper pump 1; Copper transporting ATPase 1…

Compound Information

Name monocrotophos
CAS

Reference List

PubMed Abstract RScore(About this table)
15031937 Wei X, Ru S, Jiang M, Li Y: [Effect of monocrotophos on Na+/K (+)-ATPase activity and ultramicrostructure of Sciaenops ocellatus branchiae]. Ying Yong Sheng Tai Xue Bao. 2003 Dec;14(12):2289-94.
12(0,0,2,2) Details
17215890 Aurade R, Jayalakshmi SK, Sreeramulu K: Stimulatory effect of insecticides on partially purified P-glycoprotein ATPase from the resistant pest Helicoverpa armigera. Biochem Cell Biol. 2006 Dec;84(6):1045-50.

The partially purified Ha-Pgp ATPase was reconstituted into proteoliposomes and it was found that some insecticides, namely, monocrotophos, endosulfan, cypermethrin, fenvalerate, and methylparathion, stimulated the ATPase activity.
9(0,0,1,4) Details
15454122 Garg UK, Pal AK, Jha GJ, Jadhao SB: Haemato-biochemical and immuno-pathophysiological effects of chronic toxicity with synthetic pyrethroid, organophosphate and chlorinated pesticides in broiler chicks. Int Immunopharmacol. 2004 Dec 15;4(13):1709-22.

The total ATPase activity was enhanced (P <0.01) in fenvalerate and monocrotophos than birds in control group.
6(0,0,1,1) Details
9339739 Rahman MF, Siddiqui MK, Mustafa M: Effects of a new phosphorothionate (RPR-V) on ATPases and acetylcholinesterase in rat brain by subchronic dosing. J Appl Toxicol. 1997 Sep-Oct;17(5):273-8.


Females were more susceptible with regard to brain AChE, but the reverse was seen with Mg2+-ATPase, suggesting sexual dimorphism.
1(0,0,0,1) Details
16872049 Singh M, Sandhir R, Kiran R: Erythrocyte antioxidant enzymes in toxicological evaluation of commonly used organophosphate pesticides. Indian J Exp Biol. 2006 Jul;44(7):580-3.

Present work is designed to study the in vitro effects of some organophosphates (ethion, chlorpyrifos, dimethoate and monocrotophos) on rat erythrocytes.
Membrane bound enzymes like acetylcholinesterase (AChE), Na (+)-K (+)-ATPase and Ca (2+)-ATPase were also inhibited.
1(0,0,0,1) Details
11023690 Rahman MF, Siddiqui MK, Jamil K: Inhibition of acetylcholinesterase and different ATPases by a novel phosphorothionate (RPR-II) in rat brain. Ecotoxicol Environ Saf. 2000 Oct;47(2):125-9.


The relative sensitivities of these enzymes indicated that brain AChE was more sensitive than any of the ATPases, but among the ATPases Na (+)-K (+) ATPase was more susceptible than Ca (2+) or Mg (2+) ATPases.
1(0,0,0,1) Details