Protein Information

Name IkappaBalpha
Synonyms I kappa B alpha; Mad3; IKB alpha; IKBA; IKBalpha; IkappaBalpha; Inhibitor of kappa light chain gene enhancer in B cells alpha; MAD 3…

Compound Information

Name niclosamide
CAS

Reference List

PubMed Abstract RScore(About this table)
20215516 Jin Y, Lu Z, Ding K, Li J, Du X, Chen C, Sun X, Wu Y, Zhou J, Pan J: Antineoplastic mechanisms of niclosamide in acute myelogenous leukemia stem cells: inactivation of the NF-kappaB pathway and generation of reactive oxygen species. Cancer Res. 2010 Mar 15;70(6):2516-27. Epub 2010 Mar 9.

Niclosamide inhibited the steps TAK1--> IkappaB kinase (IKK) and IKK--> IkappaBalpha.
82(1,1,1,2) Details