Protein Information

Name IGFBP 5
Synonyms IBP 5; IBP5; IGF binding protein 5; IGFBP 5; IGFBP5; Insulin like growth factor binding protein 5; Insulin like growth factor binding protein 5 precursor; IGF binding protein 5s…

Compound Information

Name nitrofen
CAS 2,4-dichloro-1-(4-nitrophenoxy)benzene

Reference List

PubMed Abstract RScore(About this table)
19844724 Ruttenstock E, Doi T, Dingemann J, Puri P: Downregulation of insulin-like growth factor binding protein 3 and 5 in nitrofen-induced pulmonary hypoplasia. Pediatr Surg Int. 2010 Jan;26(1):59-63.

CONCLUSION: Downregulation of IGFBP-3 and IGFBP-5 gene expression may cause pulmonary hypoplasia in the nitrofen-induced CDH model by interfering with retinoid signaling pathway.
45(0,1,3,5) Details