Protein Information

Name GATA4
Synonyms GATA binding factor 4; GATA binding protein 4; GATA 4; GATA4; Transcription factor GATA 4; GATA binding protein 4s; Transcription factor GATA 4s

Compound Information

Name nitrofen
CAS 2,4-dichloro-1-(4-nitrophenoxy)benzene

Reference List

PubMed Abstract RScore(About this table)
18280291 Takayasu H, Sato H, Sugimoto K, Puri P: Downregulation of GATA4 and GATA6 in the heart of rats with nitrofen-induced diaphragmatic hernia. J Pediatr Surg. 2008 Feb;43(2):362-6.

To test the hypothesis that expression of GATA4 and GATA6 is reduced in early stages of gestation in a CDH hypoplastic heart, we investigated the expression of GATA4 and GATA6 in the hearts of nitrofen-treated rats in early gestation.
108(0,3,5,8) Details
19853750 Doi T, Sugimoto K, Puri P: Prenatal retinoic acid up-regulates pulmonary gene expression of COUP-TFII, FOG2, and GATA4 in pulmonary hypoplasia. J Pediatr Surg. 2009 Oct;44(10):1933-7.

CONCLUSIONS: Up-regulation of pulmonary gene expression of COUP-TFII, FOG2, and GATA4 after prenatal treatment with retinoic acid in the nitrofen model of CDH suggests that RA may have a therapeutic potential in modulating lung growth.
11(0,0,1,6) Details