| Name | Retinal dehydrogenase 2 |
|---|---|
| Synonyms | ALDH1A2; Aldehyde dehydrogenase family 1 member A2; RALDH 2; RALDH(II); RALDH2; RALDH2 T; Retinal dehydrogenase 2; Retinaldehyde dehydrogenase 2… |
| Name | nitrofen |
|---|---|
| CAS | 2,4-dichloro-1-(4-nitrophenoxy)benzene |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 14729516 | Babiuk RP, Thebaud B, Greer JJ: Reductions in the incidence of nitrofen-induced diaphragmatic hernia by and Am J Physiol Lung Cell Mol Physiol. 2004 May;286(5):L970-3. Epub 2004 Jan 16. This includes findings that nitrofen, which induces CDH in rodents, inhibits the key enzyme for (RA) production, retinaldehyde dehydrogenase-2 (RALDH2) in vitro. |
163(2,2,2,3) | Details |
| 17203325 | Nakazawa N, Takayasu H, Montedonico S, Puri P: Altered regulation of synthesis in nitrofen-induced hypoplastic lung. Pediatr Surg Int. 2007 May;23(5):391-6. Recently, it was reported that nitrofen may act by inhibiting RALDH2. |
113(1,2,2,3) | Details |
| 12547725 | Mey J, Babiuk RP, Clugston R, Zhang W, Greer JJ: Retinal dehydrogenase-2 is inhibited by compounds that induce congenital diaphragmatic hernias in rodents. Am J Pathol. 2003 Feb;162(2):673-9. The following compounds all induce posterolateral defects in the rat diaphragm; nitrofen, 4-biphenyl carboxylic acid, bisdiamine, and SB-210661. |
3(0,0,0,3) | Details |
| 17270546 | Nakazawa N, Montedonico S, Takayasu H, Paradisi F, Puri P: Disturbance of transportation causes nitrofen-induced hypoplastic lung. J Pediatr Surg. 2007 Feb;42(2):345-9. Reverse transcriptase-polymerase chain reaction was performed to evaluate the relative amount of cellular -biding protein I, retinal dehydrogenase 1a2 and 1a3 (Aldh1a2 and Aldh1a3), receptors alpha and beta (RARalpha, RARbeta), and retinoid X receptor alpha (RXRalpha) expression in the lung. |
1(0,0,0,1) | Details |