| Name | estrogen receptor alpha |
|---|---|
| Synonyms | ER; ERA; ER alpha; ERalpha; ESR; ESR 1; ESR1; ESRA… |
| Name | cresol |
|---|---|
| CAS | methylphenol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18310895 | Satoh K, Nonaka R, Ohyama K, Nagai F, Ogata A, Iida M: Endocrine disruptive effects of chemicals eluted from nitrile-butadiene rubber gloves using reporter gene assay systems. Biol Pharm Bull. 2008 Mar;31(3):375-9. In this study, we examined the endocrine-disrupting effects of these chemicals via androgen receptor (AR) and estrogen receptor (ER)-mediated pathways using stably transfected reporter gene cell lines expressing AR (AR-EcoScreen system) and ER (MVLN cells), respectively. |
1(0,0,0,1) | Details |
| 18439640 | Furuta C, Suzuki AK, Watanabe G, Li C, Taneda S, Taya K: Nitrophenols isolated from diesel exhaust particles promote the growth of MCF-7 breast adenocarcinoma cells. Toxicol Appl Pharmacol. 2008 Aug 1;230(3):320-6. Epub 2008 Mar 10. To further investigate transcriptional activity through the estrogen receptor, MCF-7 cells were transfected with a receptor gene that allowed expression of luciferase enzyme under the control of the regulatory element. |
1(0,0,0,1) | Details |
| 17941731 | Terasaki M, Shiraishi F, Fukazawa H, Makino M: Occurrence and estrogenicity of phenolics in paper-recycling process water: pollutants originating from thermal paper in waste paper. Environ Toxicol Chem. 2007 Nov;26(11):2356-66. The estrogenicities of the identified compounds were assessed by yeast two-hybrid assays incorporating either the human or medaka fish (Oryzias latipes) estrogen receptor alpha (hERalpha and medERalpha, respectively) and an estrogen receptor competitive enzyme-linked immunosorbent assay (ER-ELISA) both with and without metabolic activation by a rat liver S9 mix. |
1(0,0,0,1) | Details |
| 16280211 | Terasaka S, Inoue A, Tanji M, Kiyama R: Expression profiling of -responsive genes in breast cancer cells treated with alkylphenols, chlorinated phenols, parabens, or bis- and benzoylphenols for evaluation of estrogenic activity. Toxicol Lett. 2006 May 25;163(2):130-41. Epub 2005 Nov 8. By selecting a set of 120 genes showing greater statistical reliability for a more reliable assay for each of the chemicals was achieved and, for the chemicals for which data were available, the results were consistent with those of previously reported estrogen receptor-binding and yeast two-hybrid assays except for chlorinated and few other phenols. |
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| 17583877 | Noguchi K, Toriba A, Chung SW, Kizu R, Hayakawa K: Identification of estrogenic/anti-estrogenic compounds in diesel exhaust particulate extract. Biomed Chromatogr. 2007 Nov;21(11):1135-42. After separating DEPE into 11 fractions by liquid-liquid extraction, the neutral fraction (N) showed anti-estrogenic activity and the weak acid fraction (WA (P)) showed estrogenic and anti-estrogenic activities by a yeast two-hybrid assay system expressing human estrogen receptor alpha. |
1(0,0,0,1) | Details |