Protein Information

Name CYP2C9
Synonyms (R) limonene 6 monooxygenase; Xenobiotic monooxygenase; Mephenytoin 4 hydroxylase; Microsomal monooxygenase; S mephenytoin 4 hydroxylase; (S) limonene 6 monooxygenase; (S) limonene 7 monooxygenase; CPC 9…

Compound Information

Name disulfoton
CAS

Reference List

PubMed Abstract RScore(About this table)
14977868 Usmani KA, Karoly ED, Hodgson E, Rose RL: In vitro sulfoxidation of thioether compounds by human cytochrome P450 and flavin-containing monooxygenase isoforms with particular reference to the CYP2C subfamily. Drug Metab Dispos. 2004 Mar;32(3):333-9.

Moreover, sulfaphenazole, a CYP2C9 competitive inhibitor, inhibited disulfoton sulfoxidation by CYP2C9 (IC50 0.84 microM) as well as in HLMs.
31(0,1,1,1) Details