| Name | progesterone receptor |
|---|---|
| Synonyms | NR3C3; PGR; PR; Progesterone receptor; Progesterone receptors |
| Name | vinclozolin |
|---|---|
| CAS | 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16504050 | Buckley J, Willingham E, Agras K, Baskin LS: Embryonic exposure to the fungicide vinclozolin causes virilization of females and alteration of progesterone receptor expression in vivo: an experimental study in mice. Environ Health. 2006 Feb 21;5:4. |
30(0,0,5,5) | Details |
| 14579009 | Scippo ML, Argiris C, Van De Weerdt C, Muller M, Willemsen P, Martial J, Maghuin-Rogister G: Recombinant human androgen and progesterone receptors for detection of potential endocrine disruptors. Anal Bioanal Chem. 2004 Feb;378(3):664-9. Epub 2003 Oct 25. The tested chemicals are organochlorine insecticides (DDT and its metabolites, methoxychlor, aldrin, dieldrin, chlordecone, lindane, trichlorobenzene), estrogenic insecticides (endosulfan, toxaphene, nonachlor), herbicides (alachlor and atrazine), fungicides (benomyl and vinclozolin), industrial chemicals (nonylphenol, bisphenol A, diphenylphtalate), antioxidants (butylated hydroxyanisol) and some phytoestrogens. |
2(0,0,0,2) | Details |
| 12215663 | O'Connor JC, Frame SR, Ladics GS: Evaluation of a 15-day screening assay using intact male rats for identifying antiandrogens. Toxicol Sci. 2002 Sep;69(1):92-108. CPA caused effects consistent with its mixed AR antagonist/progesterone receptor agonist activity: it decreased ASG weights, caused hormonal alterations (increased T and E2; decreased FSH), and caused spermatid retention. |
1(0,0,0,1) | Details |
| 8845038 | Laws SC, Carey SA, Kelce WR, Cooper RL, Gray LE Jr: Vinclozolin does not alter progesterone receptor (PR) function in vivo despite inhibition of PR binding by its metabolites in vitro. Toxicology. 1996 Sep 2;112(3):173-82. |
0(0,0,0,0) | Details |