| Name | serum cholinesterase |
|---|---|
| Synonyms | Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase… |
| Name | disulfoton |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 2304190 | White DH, Seginak JT: Brain cholinesterase inhibition in songbirds from pecan groves sprayed with phosalone and disulfoton. J Wildl Dis. 1990 Jan;26(1):103-6. |
88(1,1,2,3) | Details |
| 8449387 | Llorens J, Crofton KM, Tilson HA, Ali SF, Mundy WR: Characterization of disulfoton-induced behavioral and neurochemical effects following repeated exposure. Fundam Appl Toxicol. 1993 Feb;20(2):163-9. These experiments examined the relationship between behavioral alterations and neurochemical changes in rats exposed repeatedly to disulfoton, an organophosphate cholinesterase inhibitor. |
31(0,1,1,1) | Details |
| 7150362 | Costa LG, Schwab BW, Murphy SD: Differential alterations of cholinergic muscarinic receptors during chronic and acute tolerance to organophosphorus insecticides. Biochem Pharmacol. 1982 Nov 1;31(21):3407-13. Male mice treated for 2 weeks with the anticholinesterase insecticide disulfoton (O,O-diethyl S-[2-(ethylthio)-ethyl] phosphorodithioate; 10 mg per kg per day) became tolerant to the hypothermic and antinociceptive effects of disulfoton itself and of oxotremorine, a muscarinic cholinergic agonist. |
31(0,1,1,1) | Details |
| 10403662 | Jones RD, Hastings TF, Landes AM: Absence of neurovisual effects due to tissue and blood cholinesterase depression in a chronic disulfoton feeding study in dogs. Toxicol Lett. 1999 Jun 1;106(2-3):181-90. |
11(0,0,1,6) | Details |
| 6642106 | Costa LG, Murphy SD: Unidirectional cross-tolerance between the insecticide propoxur and the organophosphate disulfoton in mice. Fundam Appl Toxicol. 1983 Sep-Oct;3(5):483-8. Mice tolerant to propoxur were cross-tolerant to the hypothermic and anticholinesterase effects of disulfoton. |
7(0,0,1,2) | Details |
| 8212012 | Ward TR, Ferris DJ, Tilson HA, Mundy WR: Correlation of the anticholinesterase activity of a series of organophosphates with their ability to compete with agonist binding to muscarinic receptors. Toxicol Appl Pharmacol. 1993 Oct;122(2):300-7. Echothiophate and DFP were potent inhibitors of [3H] CD binding, as were the active "oxon" forms of parathion, malathion, and disulfoton. |
4(0,0,0,4) | Details |
| 3020234 | Costa LG, Kaylor G, Murphy SD: Carbachol- and -stimulated phosphoinositide metabolism in rat brain: effect of chronic cholinesterase inhibition. J Pharmacol Exp Ther. 1986 Oct;239(1):32-7. In this study we have investigated whether repeated administration of the organophosphorus insecticide disulfoton, known to cause the development of tolerance to this compound, would affect phosphoinositide metabolism in rat brain. |
1(0,0,0,1) | Details |
| 4209143 | Smith RL: The estimation of serum cholinesterase in the presence of anti-cholinesterase insecticides. Clin Chim Acta. 1974 May 17;52(3):315-9. |
1(0,0,0,1) | Details |
| 4154787 | Stevens JT, Greene FE: Alteration of hepatic microsomal metabolism of male mice by certain anticholinesterase insecticides. Bull Environ Contam Toxicol. 1974 Jun;11(6):538-44. |
1(0,0,0,1) | Details |
| 3820777 | Shimada E, Yoshida M, Yamanaka S, Aoyama H, Yamamura Y: [Erythrocyte and plasma cholinesterase activities on poisoning by disyston, fenitrothion and malathion] Sangyo Igaku. 1986 Sep;28(5):368-9. |
1(0,0,0,1) | Details |
| 675690 | Robinson CP, Smith PW, Endecott BR: Depression of cholinesterase activity by ethylestrenol in organophosphorus-poisoned and normal rats. Toxicol Appl Pharmacol. 1978 Apr;44(1):207-11. |
1(0,0,0,1) | Details |
| 6636179 | Schwab BW, Costa LG, Murphy SD: Muscarinic receptor alterations as a mechanism of anticholinesterase tolerance. Toxicol Appl Pharmacol. 1983 Oct;71(1):14-23. Tolerance to the toxic signs of the organophosphorus ester acetylcholinesterase inhibitor, O,O-diethyl S-[2-(ethylthio) ethyl] phosphorodithioate (disulfoton), was induced in rats by giving 10 doses of 2.0 mg/kg/day. |
1(0,0,0,1) | Details |
| 3914075 | Xue SZ, Ding XJ, Ding Y: Clinical observation and comparison of the effectiveness of several oxime cholinesterase reactivators. Scand J Work Environ Health. 1985;11 Suppl 4:46-8. |
3(0,0,0,3) | Details |
| 9024678 | Sheets LP, Hamilton BF, Sangha GK, Thyssen JH: Subchronic neurotoxicity screening studies with six organophosphate insecticides: an assessment of behavior and morphology relative to cholinesterase inhibition. Fundam Appl Toxicol. 1997 Jan;35(1):101-19. Sulprofos, disulfoton, azinphos-methyl, methamidophos, trichlorfon, and tebupirimphos were screened for potential, in accordance with U.S. |
2(0,0,0,2) | Details |
| 973741 | Felsenstein WC, Staiff DC, Miller GC: Acute demeton poisoning in a child. Arch Environ Health. 1976 Sep-Oct;31(5):266-9. Plasma (pseudo) cholinesterase levels 15 to 41 hours after exposure ranged from 0.24 to 0.48 international units (IU). |
2(0,0,0,2) | Details |
| 17423767 | Frank R, Braun HE, Wilkie I, Ewing R: A review of insecticide poisonings among domestic livestock in southern Ontario, Canada, 1982-1989. Can Vet J. 1991 Apr;32(4):219-226. Signs typical of cholinesterase inhibition caused by organophosphorus poisoning were observed in most cases. From 1982 to 1989, inclusive, 20 poisonings were investigated by the Ontario Ministry of Agriculture and Food following ingestion by domestic livestock of granular insecticides including terbufos (13 poisonings), disulfoton (two poisonings), fonofos (two poisonings), phorate (two poisonings), and carbofuran (one poisoning); all are used for rootworm (Diabrotica spp.) control in corn. |
2(0,0,0,2) | Details |
| 16189388 | von Mach MA, Weilemann LS, von Landenberg P: Pseudocholinesterase activity in organophosphate poisoning after storage of unseparated blood samples at room temperature for 3 weeks. Clin Chem. 2005 Oct;51(10):1907-8. |
1(0,0,0,1) | Details |
| 6609006 | Costa LG, Shao M, Basker K, Murphy SD: Chronic administration of an organophosphorus insecticide to rats alters cholinergic muscarinic receptors in the pancreas. Chem Biol Interact. 1984 Mar;48(3):261-9. Male rats were treated for 10 days with the organophosphorus insecticide, acetylcholinesterase inhibitor, O,O-diethyl S-[2-(ethylthio) ethyl] phosphorodithioate (disulfoton, 2 mg/kg/day by gavage). At the end of the treatment, binding of [3H] quinuclidinyl benzilate ( [3H] QNB) to cholinergic muscarinic receptors and cholinesterase (ChE) activity were assayed in the pancreas. |
1(0,0,0,1) | Details |
| 7328703 | Schwab BW, Murphy SD: Induction of anticholinesterase tolerance in rats with doses of disulfoton that produce no cholinergic signs. J Toxicol Environ Health. 1981 Jul-Aug;8(1-2):199-204. The induction of anticholinesterase tolerance has, in the past, been achieved by using multiple doses of organophosphorus ester insecticides that initially caused cholinergic signs. |
1(0,0,0,1) | Details |
| 4829227 | Westfall DP, McPhillips JJ, Foley DJ: Inhibition of cholinesterase activity after postganglionic denervation of the rat vas deferens: evidence for prejunctional supersensitivity to J Pharmacol Exp Ther. 1974 May;189(2):493-8. |
1(0,0,0,1) | Details |
| 674813 | Holt TM, Hawkins RK: Rat hippocampal response to cholinesterase inhibition. . Res Commun Chem Pathol Pharmacol. 1978 May;20(2):239-51. In this study, 13 groups of rats were injected with the insecticide Disulfoton (0-0-diethyl S-2-[(ethylthio) ethyl] phosphorodithioate), sacrificed after various time intervals and levels of hippocampal determined. |
2(0,0,0,2) | Details |
| 16962835 | Poyot T, Nachon F, Froment MT, Loiodice M, Wieseler S, Schopfer LM, Lockridge O, Masson P: Mutant of Bungarus fasciatus acetylcholinesterase with low affinity and low hydrolase activity toward organophosphorus esters. Biochim Biophys Acta. 2006 Sep;1764(9):1470-8. Epub 2006 Aug 4. Bungarus fasciatus acetylcholinesterase (BfAChE) was engineered to acquire organophosphate hydrolase (OPase) activity by reproducing the features of the human butyrylcholinesterase G117H mutant, the first mutant designed to hydrolyse OPs. |
2(0,0,0,2) | Details |
| 6510327 | Hill EF, Camardese MB: Toxicity of anticholinesterase insecticides to birds: technical grade versus granular formulations. Ecotoxicol Environ Saf. 1984 Dec;8(6):551-63. The test chemicals were Amaze 15G (isofenphos), Counter 15G (terbufos), Dasanit 15G (fensulfothion), Diazinon 14G (diazinon), Di-Syston 15G (disulfoton), Dyfonate 20G (fonofos), Furadan 10G (carbofuran), Lorsban 15G (chlorpyrifos), Nemacur 15G (fenamiphos), Parathion 10G (parathion), Tattoo 10G (bendiocarb), Temik 15G (aldicarb), and Thimet 15G (phorate). |
2(0,0,0,2) | Details |
| 4764290 | Foley DJ, McPhillips JJ: Response of the rat ileum, uterus and vas deferens to carbachol and following repeated daily administration of a cholinesterase inhibitor. Br J Pharmacol. 1973 Jul;48(3):418-25. Daily i.p. administration, for eight days, of the cholinesterase inhibitor disulfoton to rats produced mild to moderate signs of intoxication (tremors, incontinence and diarrhoea) but no deaths.2. |
1(0,0,0,1) | Details |
| 7897754 | Futagami K, Otsubo K, Nakao Y, Aoyama T, Iimori E, Urakami S, Ide M, Oishi R: Acute organophosphate poisoning after disulfoton ingestion. J Toxicol Clin Toxicol. 1995;33(2):151-5. Pralidoxime iodide administration temporarily restored erythrocyte cholinesterase activity to almost normal and inhibited the excessive, delayed reduction of cholinesterase activity. |
1(0,0,0,1) | Details |
| 239213 | Lefever GS, Green RD: The effects of chronic ganglion blockade and chronic cholinesterase inhibition on the sensitivity of rabbit stomach muscularis to cholinergic and adrenergic agonists. J Pharmacol Exp Ther. 1975 Jun;193(3):739-47. The EC50 values, KA values and efficacies (e) of selected agonists have been determined in strips of stomach muscularis from control, chlorisondamine-pretreated and O, O-diethyl S [2 (ethylthio) ethyl] phosphodithioate (disulfoton)-pretreated rabbits. |
1(0,0,0,1) | Details |