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Lemos MF, Esteves AC, Samyn B, Timperman I, van Beeumen J, Correia A, van Gestel CA, Soares AM: Protein differential expression induced by endocrine disrupting compounds in a terrestrial isopod. Chemosphere. 2010 Apr;79(5):570-6. Epub 2010 Mar 1.
We have used a dose/response approach to unravel the protein expression in different organs of isopods exposed to bisphenol A (BPA) and vinclozolin (Vz) and assess their potential use as surrogate species. EDCs affected proteins involved in the energy metabolism (arginine kinase), proteins of the heat shock protein family (Hsp70 and GRP78) and most likely microtubule dynamics (tubulin). |
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