Protein Information

Name thyroid peroxidase
Synonyms MSA; TPO; TPO protein; TPX; Thyroid microsomal antigen; Thyroid peroxidase; Thyroid peroxidase isoform d variant; Thyroid peroxidase precursor…

Compound Information

Name potassium thiocyanate
CAS potassium thiocyanate

Reference List

PubMed Abstract RScore(About this table)
12325367 Coval ML, Taurog A: Purification and iodinating activity of hog thyroid peroxidase. J Biol Chem. 1967 Dec 10;242(23):5510-23.

1(0,0,0,1) Details
11241400 Manzon RG, Holmes JA, Youson JH: Variable effects of goitrogens in inducing precocious metamorphosis in sea lampreys (Petromyzon marinus). J Exp Zool. 2001 Apr 15;289(5):290-303.

Two of these goitrogens (propylthiouracil [PTU] and methimazole [MMI]) are inhibitors of thyroid peroxidase-catalyzed iodination, and three (potassium perchlorate [KClO (4)], potassium thiocyanate [KSCN], and sodium perchlorate [NaClO (4)]) are anionic competitors of iodide uptake.
81(1,1,1,1) Details
6706930 Magnusson RP, Taurog A, Dorris ML: Mechanism of iodide-dependent catalatic activity of thyroid peroxidase and lactoperoxidase. J Biol Chem. 1984 Jan 10;259(1):197-205.

3(0,0,0,3) Details