Protein Information

Name HSP27
Synonyms DMPK binding protein; HSP27; HSPB 2; HSPB2; Heat shock 27kD protein 2; Heat shock protein beta 2; Hs.78846; MKBP…

Compound Information

Name malathion
CAS diethyl 2-[(dimethoxyphosphinothioyl)thio]butanedioate

Reference List

PubMed Abstract RScore(About this table)
19607909 Ahmed T, Tripathi AK, Suke SG, Kumar V, Ahmed RS, Das S, Banerjee BD: Role of HSP27 and reduced glutathione in modulating malathion-induced apoptosis of human peripheral blood mononuclear cells: ameliorating effect of N-acetylcysteine and curcumin. Toxicol In Vitro. 2009 Oct;23(7):1319-25. Epub 2009 Jul 14.

In low doses, malathion caused mild depletion of GSH, threefold increase in HSP27 level and a range bound cytotoxicity and apoptosis of PBMC.
75(0,2,4,5) Details