Protein Information

Name glutamyl transpeptidase
Synonyms CD224; CD224 antigen; D22S672; D22S732; GGT; GGT 1; GGT1; GGT1 protein…

Compound Information

Name malathion
CAS diethyl 2-[(dimethoxyphosphinothioyl)thio]butanedioate

Reference List

PubMed Abstract RScore(About this table)
2878643 Lechner DW, Abdel-Rahman MS: The effect of carbaryl and malathion in combination on gamma-glutamyl transpeptidase and glutathione S-alkyltransferase activity in vitro. Arch Environ Contam Toxicol. 1986 Nov;15(6):647-51.
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10414779 Banerjee BD, Seth V, Bhattacharya A, Pasha ST, Chakraborty AK: Biochemical effects of some pesticides on lipid peroxidation and free-radical scavengers. Toxicol Lett. 1999 Jun 30;107(1-3):33-47.

Oxidative stress was studied in blood samples obtained from lindane, malathion and propoxur poisoning cases admitted to the Guru Teg Bahadur Hospital, Delhi and evaluated for lipid peroxidation, oxygen free radical (OFR) scavenging enzymes, and glutathione (GSH) and related enzymes.
Acetylcholine esterase (AChE), gamma glutamyl transpeptidase (GGT) and GSH level were also assayed in lymphocytes.
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2430350 Kashyap SK: Health surveillance and biological monitoring of pesticide formulators in India. Toxicol Lett. 1986 Oct;33(1-3):107-14.

Exposure of 160 workers to a combination of pesticides (malathion, parathion, DDT and HCH) resulted in 73% of the workers showing toxic signs and symptoms.
Changes in the liver enzymes ornithine carbamyl transferase (OCT), gamma-glutamyl transpeptidase (GGTP), leucine aminopeptidase (LAP) and in immunoglobulin M (IgM) showed possible effects on liver and humoral immunity.
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11522282 Seth V, Banerjee BD, Bhattacharya A, Pasha ST, Chakravorty AK: Pesticide induced alterations in acetylcholine esterase and gamma glutamyl transpeptidase activities and glutathione level in lymphocytes of human poisoning cases. Clin Biochem. 2001 Jul;34(5):427-9.

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