Protein Information

Name Potassium channel (protein family or complex)
Synonyms Potassium channel

Compound Information

Name sodium azide
CAS sodium azide

Reference List

PubMed Abstract RScore(About this table)
18678543 Kung FL, Tsai JL, Lee CH, Lou KL, Tang CY, Liou HH, Lu KL, Chen YH, Wang WJ, Tsai MC: Effects of sodium azide, barium ion, d-amphetamine and procaine on inward rectifying potassium channel 6.2 expressed in Xenopus oocytes. J Formos Med Assoc. 2008 Aug;107(8):600-8.
7(0,0,1,2) Details
19136734 Law JK, Yeung CK, Hofmann B, Ingebrandt S, Rudd JA, Offenhausser A, Chan M: The use of microelectrode array (MEA) to study the protective effects of potassium channel openers on metabolically compromised HL-1 cardiomyocytes. Physiol Meas. 2009 Feb;30(2):155-67. Epub 2009 Jan 9.

Beat frequency and extracellular action potential (exAP) amplitude were measured in the presence of metabolic inhibitors (sodium azide (NaN (3)) or 2-deoxyglucose (2-DG)) or KCOs (pinacidil (PIN, a cyanoguanidine derivative, activates sarcolemmal K (ATP) channels) or SDZ PCO400 (SDZ, a benzopyran derivative, activates mitochondrial K (ATP) channels)).
2(0,0,0,2) Details
8834104 Chao KF, Liu SH, Lin-Shiau SY: Suppression of potassium currents by cyanide on the mouse motor nerve terminals. Neurosci Lett. 1996 Jan 19;203(2):105-8.


NaCN at low concentrations markedly depressed the potassium currents in the motor nerve terminal of mouse triangularis sterni neuromuscular junction pretreated with potassium channel blockers 4-aminopyridine (4-AP), tetraethylammonium (TEA) or glucose-free medium.
1(0,0,0,1) Details
9603910 Branstrom R, Efendic S, Berggren PO, Larsson O: Direct inhibition of the pancreatic beta-cell ATP-regulated potassium channel by alpha-ketoisocaproate. J Biol Chem. 1998 Jun 5;273(23):14113-8.

In the presence of the metabolic inhibitor sodium azide, alpha-ketoisocaproate was still able to inhibit single channel activity in excised patches and to block whole cell KATP currents in intact cells.
1(0,0,0,1) Details
11374879 Denda M, Ashida Y, Inoue K, Kumazawa N: Skin surface electric potential induced by ion-flux through epidermal cell layers. Biochem Biophys Res Commun. 2001 Jun 1;284(1):112-7.


Skin surface barrier disruption reduced the potential and calcium and potassium channel blockers partially prevented the decrease.
1(0,0,0,1) Details
9705995 Lee K, Dixon AK, Freeman TC, Richardson PJ: Identification of an ATP-sensitive potassium channel current in rat striatal cholinergic interneurones. J Physiol. 1998 Jul 15;510 ( Pt 2):441-53.

Using permeabilized patch recordings, neurones were shown to hyperpolarize in response to glucose deprivation or metabolic poisoning with sodium azide (NaN3).
1(0,0,0,1) Details