Protein Information

Name acid phosphatase
Synonyms ACP 3; PAP; ACP3; ACPP; ACPP protein; Acid phosphatase; Acid phosphatase prostate nirs variant 1; PACP…

Compound Information

Name malathion
CAS diethyl 2-[(dimethoxyphosphinothioyl)thio]butanedioate

Reference List

PubMed Abstract RScore(About this table)
17974266 Zhang YL, Mu W, Chen ZL, Han ZR, Ma C, Zhai RH: [Susceptibility and related physiological and biochemical mechanisms of Carposina niponensis Walsingham larvae on six insecticides before and after overwintering]. Ying Yong Sheng Tai Xue Bao. 2007 Aug;18(8):1913-6.

The study with impregnating method showed that after overwintering, the susceptibility of Carposina niponensis larvae on triazophos, phoxim, chlorpyrifos, malathion, lambda-cyhalothrin and abamectin was 34.50, 16.71, 3.89, 3.28, 5.90 and 2.73 times as much as that before overwintering, the total protein, glycogen and fat contents and carboxylesterase, acid phosphatase, alkaline phosphatase, glutathione-S-transferase, superoxide dismutase, catalase and peroxidase activities in C. niponensis larvae were decreased by 17.10%, 41.76% and 30.08%, 62.36%, 53.47%, 76.19%, 80.60%, 18.77%, 14.16% and 64.02%, respectively, and the activity of acetylcholinesterase, the target enzyme of many insecticides, was 1.41 times as much as that before overwintering.
31(0,1,1,1) Details
7112611 Saigal S, Bhatnagar VK, Malviya AN: Effect of selected pesticides on alkaline and acid phosphatase in the rat. Toxicol Lett. 1982 Jul;12(2-3):177-80.

Elsan induced an increase in acid phosphatase activity in liver, kidney and intestine whereas the response to DDT, malathion and phosalone was variable.
7(0,0,1,2) Details
2126808 Jabbar A, Khawaja SA, Iqbal A, Malik SA: Effect of malathion and methyl-parathion on rat liver enzymes. J Pak Med Assoc. 1990 Nov;40(11):266-70.

Short term (24 hr.) and long term (4 weeks) treatment with insecticides resulted in increased specific activities of liver enzymes, Acid phosphatase, Alkaline phosphatase, Glutamate dehydrogenase, Glutamate oxaloacetate transaminase and Glutamate pyruvate transaminase.
1(0,0,0,1) Details
2126817 Jabbar A, Khawaja SA, Iqbal A, Malik SA: Effect of malathion and methyl-parathion on rat liver enzymes. J Pak Med Assoc. 1990 Apr;40(4):85-9.

Short term (24 hr) and long term (4 weeks) treatment with insecticides resulted in increased specific activities of liver enzymes, Acid phosphatase, Alkaline phosphatase, Glutamate dehydrogenase, Glutamate oxaloacetate transaminase and Glutamate pyruvate transaminase.
1(0,0,0,1) Details
15631514 Hoehamer CF, Mazur CS, Wolfe NL: Purification and partial characterization of an acid phosphatase from Spirodela oligorrhiza and its affinity for selected organophosphate pesticides. J Agric Food Chem. 2005 Jan 12;53(1):90-7.

Furthermore, analysis using capillary electrophoresis demonstrated that this hydrolytic enzyme could transform a wide array of organophosphate pesticides including S-2-ethylthioethyl O,O-dimethylphosphorothioate (demeton-S-methyl); S-1,2-bis (ethoxycarbonyl) ethyl O,O-dimethylphosphorodithioate (malathion); O,O-dimethyl O-4-nitrophenyl (paraoxon); O,O,O,O-tetraethyldithiopyrophosphate (sulfatep); O-2-chloro-4-nitrophenyl O,O-dimethylphosphorothioate (dicapthon); and 2,2-dichlorovinyl dimethylphosphate (dichlorvos).
7(0,0,0,7) Details
18831386 Choudhary N, Goyal R, Joshi SC: Effect of malathion on reproductive system of male rats. J Environ Biol. 2008 Mar;29(2):259-62.

The activity of testicular enzyme acid phosphatase increased significantly while decreased alkaline phosphatase activity was found.
1(0,0,0,1) Details