Protein Information

Name HEMA
Synonyms AHF; Antihemophilic factor; Coagulation factor VIII; Coagulation factor VIII precursor; DXS1253E; F8; F8 protein; F8B…

Compound Information

Name mercuric chloride
CAS

Reference List

PubMed Abstract RScore(About this table)
16691427 Reichl FX, Esters M, Simon S, Seiss M, Kehe K, Kleinsasser N, Folwaczny M, Glas J, Hickel R: Cell death effects of resin-based dental material compounds and mercurials in human gingival fibroblasts. Arch Toxicol. 2006 Jun;80(6):370-7. Epub 2005 Nov 17.

In order to test the hypothesis that released dental restorative materials can reach toxic levels in human oral tissues, the cytotoxicities of the resin-based dental (co) monomers hydroxyethylmethacrylate (HEMA), triethyleneglycoldimethacrylate (TEGDMA), urethanedimethacrylate (UDMA), and bisglycidylmethacrylate (BisGMA) compared with methyl mercury chloride (MeHgCl) and the amalgam component mercuric chloride (HgCl2) were investigated on human gingival fibroblasts (HGF) using two different test systems: (1) the modified XTT-test and (2) the modified H 33342 staining assay.
35(0,1,1,5) Details
11163377 Reichl FX, Walther UI, Durner J, Kehe K, Hickel R, Kunzelmann KH, Spahl W, Hume WR, Benschop H, Forth W: Cytotoxicity of dental composite components and mercury compounds in lung cells. Dent Mater. 2001 Mar;17(2):95-101.

OBJECTIVE: The effect of dental composite components triethyleneglycoldimethacrylate (TEGDMA) and hydroxyethylmethacrylate (HEMA), as well as mercuric chloride (HgCl2) and methylmercury chloride (MeHgCl) was investigated on the release of lactatedehydrogenase (LDH) from alveolar epithelial lung cell lines in vitro.
9(0,0,1,4) Details
11205434 Kehe K, Reichl FX, Durner J, Walther U, Hickel R, Forth W: Cytotoxicity of dental composite components and mercury compounds in pulmonary cells. Biomaterials. 2001 Feb;22(4):317-22.

The cytotoxic potentials of the dental composite components triethyleneglycoldimethacrylate (TEGDMA) and 2-hydroxy-ethylmethacrylate (HEMA) as well as mercuric chloride (HgCl2) and methyl mercury chloride (MeHgCl) were investigated.
9(0,0,1,4) Details
10550480 Reichl FX, Durner J, Muckter H, Elsenhans B, Forth W, Kunzelmann KH, Hickel R, Spahl W, Hume WR, Moes GW: Effect of dental materials on gluconeogenesis in rat kidney tubules. Arch Toxicol. 1999 Sep;73(7):381-6.

The effect of dental composite components triethyleneglycoldimethacrylate (TEGDMA) and hydroxyethylmethacrylate (HEMA) as well as mercuric chloride (HgCl (2)) and methylmercury chloride (MeHgCl) on gluconeogenesis was investigated in isolated rat kidney tubules.
9(0,0,1,4) Details
12615481 Franz-Xaver R, Jurgen D, Kai K, Matthias F, Norbert K, Markus S, El-Mahdy K, Reinhard H: Synergistic effects of H2O2 with components of dental restorative materials on gluconeogenesis in rat kidney tubules. Biomaterials. 2003 May;24(11):1909-16.

The effect of dental composite components triethyleneglycoldimethacrylate (TEGDMA) and hydroxyethylmethacrylate (HEMA) as well as mercuric chloride (HgCl (2)) and methylmercury chloride (MeHgCl), each in combination with H (2) O (2), was investigated on gluconeogenesis in kidney cells.
8(0,0,1,3) Details
12209911 Walther UI, Walther SC, Liebl B, Reichl FX, Kehe K, Nilius M, Hickel R: Cytotoxicity of ingredients of various dental materials and related compounds in L2- and A549 cells. J Biomed Mater Res. 2002;63(5):643-9.


The composite components 2-hydroxyethylmethacrylate (HEMA) and triethleneglycoldimethacrylate (TEGDMA) showed time- and concentration-dependent effects of cytotoxicity at high concentrations (about 1-5 mmol/l).
1(0,0,0,1) Details