| Name | heme oxygenase 1 |
|---|---|
| Synonyms | HMOX 1; HMOX1; HMOX1 protein; HO; HO 1; HO1; Heme oxygenase (Decycling) 1; Heme oxygenase (Decyclizing) 1… |
| Name | mercuric chloride |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9784401 | Menzel DB, Rasmussen RE, Lee E, Meacher DM, Said B, Hamadeh H, Vargas M, Greene H, Roth RN: Human lymphocyte heme oxygenase 1 as a response biomarker to inorganic arsenic. Biochem Biophys Res Commun. 1998 Sep 29;250(3):653-6. HO1 was also induced by 10 microM cadmium or mercuric chloride. |
13(0,0,1,8) | Details |
| 9544699 | Horikawa S, Ito K, Ikeda S, Shibata T, Ishizuka S, Yano T, Hagiwara K, Ozasa H, Katsuyama I: Induction of heme oxygenase-1 in toxic renal injury: mercuric chloride-induced acute renal failure in rat. Toxicol Lett. 1998 Jan 16;94(1):57-64. |
11(0,0,1,6) | Details |
| 10996484 | Yoneya R, Ozasa H, Nagashima Y, Koike Y, Teraoka H, Hagiwara K, Horikawa S: pretreatment ameliorates aspects of the nephropathy induced by mercuric chloride in the rat. Toxicol Lett. 2000 Aug 16;116(3):223-9. Heme oxygenase-1 (HO-1) is antioxidative enzyme and is known to play a protective role against the oxidative injury. |
4(0,0,0,4) | Details |
| 10544060 | Turney KD, Parrish AR, Orozco J, Gandolfi AJ: Selective activation in the MAPK pathway by Hg (II) in precision-cut rabbit renal cortical slices. Toxicol Appl Pharmacol. 1999 Nov 1;160(3):262-70. Cortical slices (275 microm) were obtained from 1.0 kg NZW rabbits and exposed to mercuric chloride [Hg (II)] at concentrations of 0.01-10 microM for 2-8 h. However, an induction of heme-oxygenase-1 (Hsp32) was seen following a 2-h challenge to Hg (II). |
1(0,0,0,1) | Details |
| 16737592 | Zhang Y, Zeng WC, Chen R, Wang SR: [Experimental research on antagonistic effect of heme oxygenase-1 on acute mercury induced renal impairment] Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2006 May;24(5):289-90. |
1(0,0,0,1) | Details |
| 16507785 | Yuen PS, Jo SK, Holly MK, Hu X, Star RA: Ischemic and nephrotoxic acute renal failure are distinguished by their broad transcriptomic responses. Physiol Genomics. 2006 May 16;25(3):375-86. Epub 2006 Feb 28. Western blotting confirmed that heme oxygenase-1 (HO-1) and activating transcription factor-3 (ATF3) proteins were upregulated; however, unexpectedly, their localization changed within the kidney. We compared rat kidney transcriptomes at 2 and 8 h after ischemia/reperfusion and after mercuric chloride. |
1(0,0,0,1) | Details |
| 9863766 | Brawer JR, McCarthy GF, Gornitsky M, Frankel D, Mehindate K, Schipper HM: Mercuric chloride induces a stress response in cultured astrocytes characterized by mitochondrial uptake of iron. Neurotoxicology. 1998 Dec;19(6):767-76. Concurrent with these changes, mercuric chloride treatment activates transcription of the heme oxygenase-1 (HO-1) gene in a dose dependent manner, further indicating an oxidative stress response. |
81(1,1,1,1) | Details |