| Name | protein tyrosine kinase |
|---|---|
| Synonyms | Acidic fibroblast growth factor; Tyrosylprotein kinase; Protein tyrosine kinase; Hydroxyaryl protein kinase; CD334; CD334 antigen; FGF receptor 4; FGFR 4… |
| Name | mercuric chloride |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 11106432 | Robbins SM, Quintrell NA, Bishop JM: Mercuric chloride activates the Src-family protein tyrosine kinase, Hck in myelomonocytic cells. Eur J Biochem. 2000 Dec;267(24):7201-8. |
81(1,1,1,1) | Details |
| 10092522 | Howlett CJ, Bisson SA, Resek ME, Tigley AW, Robbins SM: The proto-oncogene p120 (Cbl) is a downstream substrate of the Hck protein-tyrosine kinase. Biochem Biophys Res Commun. 1999 Apr 2;257(1):129-38. We have found that upon enzymatic activation of Hck by the heavy metal mercuric chloride, there was a rapid increase in the levels of phosphorylation of several proteins including the proto-oncogene p120 (Cbl). |
1(0,0,0,1) | Details |
| 7507957 | Nakashima I, Pu MY, Nishizaki A, Rosila I, Ma L, Katano Y, Ohkusu K, Rahman SM, Isobe K, Hamaguchi M, et al.: Redox mechanism as alternative to ligand binding for receptor activation delivering disregulated cellular signals. J Immunol. 1994 Feb 1;152(3):1064-71. Along with the aggregation of Thy-1 and CD4, nonreceptor protein tyrosine kinase p56lck was aggregated and activated. |
1(0,0,0,1) | Details |
| 10447931 | McCabe MJ Jr, Santini RP, Rosenspire AJ: Low and nontoxic levels of ionic mercury interfere with the regulation of cell growth in the WEHI-231 B-cell lymphoma. Scand J Immunol. 1999 Sep;50(3):233-41. WEHI-231 is a mouse B-cell line, which is a well-established model for studying signal transduction in B lymphocytes, normally responding to cross-linking of the B-cell receptor (BCR) complex by the rapid upregulation of protein tyrosine kinase activity, followed by increased intracellular and activation of protein kinase C. |
1(0,0,0,1) | Details |