Protein Information

Name interleukin 2
Synonyms Aldesleukin; IL 2; IL2; Interleukin 2; Interleukin 2 precursor; T cell growth factor; TCGF; lymphokine…

Compound Information

Name malathion
CAS diethyl 2-[(dimethoxyphosphinothioyl)thio]butanedioate

Reference List

PubMed Abstract RScore(About this table)
3051516 Rodgers KE, Leung N, Ware CF: Effects of acute administration of O,S,S-trimethyl phosphorodithioate on the generation of cellular and humoral immune responses following in vitro stimulation. Toxicology. 1988 Oct;51(2-3):241-53.

The time course of immune modulation induced by acute treatment with O,S,S-trimethyl phosphorodithioate (OSS-TMP), an impurity in technical formulations of malathion, was examined in female C57BL/6 mice.
The immune parameters studied included the generation of cytotoxic T lymphocytes (CTL) to alloantigen (H-2 incompatible) and antibody secreting cells to sheep red blood cells, proliferative response to the mitogens, and interleukin-2 (IL-2) production.
1(0,0,0,1) Details
3877352 Rodgers KE, Imamura T, Devens BH: Effects of subchronic treatment with O,O,S-trimethyl phosphorothioate on cellular and humoral immune response systems. Toxicol Appl Pharmacol. 1985 Nov;81(2):310-8.

The effect of a 14-day treatment with low doses of O,O,S-Trimethyl phosphorothioate (OOS-TMP), an impurity in technical malathion, on the generation of cell-mediated and humoral immune responses was examined in female C57B1/6 mice.
At a dose of 0.5 mg/kg/day OOS-TMP, the generation of antibody-secreting cells to sheep red blood cells (SRBC), the production of interleukin 2 (IL-2), and proliferative responses to the mitogens concanavalin A (Con A) and lipopolysaccharide (LPS) were elevated.
1(0,0,0,1) Details
2784238 Rodgers KE, Stern ML, Ware CF: Effects of subacute administration of O,S,S-trimethyl phosphorodithioate on cellular and humoral immune response systems. Toxicology. 1989 Feb;54(2):183-95.


The effects of 14-day treatment with low doses of O,S,S-trimethyl phosphorodithioate (OSS-TMP), an impurity in technical malathion, on the generation of cell-mediated and humoral immune responses were examined in female C57BL/6 mice.
0(0,0,0,0) Details
3493228 Rodgers KE, Imamura T, Devens BH: Organophosphorus pesticide immunotoxicity: effects of O,O,S-trimethyl phosphorothioate on cellular and humoral immune response systems. Immunopharmacology. 1986 Dec;12(3):193-202.

The time course of immunosuppression induced by acute treatment with O,O,S-trimethyl phosphorothioate (OOS-TMP), an impurity in technical formulations of malathion, was examined in female C57B1/6 mice.
Both cell-mediated and humoral immune responses were examined and included allospecific cytotoxic T cells, proliferative response to mitogens, interleukin-2 production and antibody production to sheep red blood cells.
2(0,0,0,2) Details