Protein Information

Name phospholipase C
Synonyms PLC L; PLCE; PLC L (PLC epsilon); PLCL; PLCL 1; PLCL1; PLDL 1; PLDL1…

Compound Information

Name mercuric chloride
CAS

Reference List

PubMed Abstract RScore(About this table)
2286355 el-Baruni K, Taylor I, Roath S, Francis JL: Factor X-activating procoagulant in normal and malignant breast tissue. Hematol Oncol. 1990 Nov-Dec;8(6):323-32.

FXAA was markedly reduced by aluminium hydroxide, barium citrate, anti-human factor VII, DFP, PMSF and phospholipase C, but was unaffected by iodoacetamide and mercuric chloride.
31(0,1,1,1) Details
7698341 Pu M, Ma L, Ohkusu K, Isobe K, Taguchi R, Ikezawa H, Hamaguchi M, Nakashima I: Direct evidence of involvement of glycosylphosphatidylinositol-anchored proteins in the heavy metal-mediated signal delivery into T lymphocytes. FEBS Lett. 1995 Mar 20;361(2-3):295-8.


This rather unusual signal delivery by HgCl2 is diminished by the pre-treatment of cells with phosphatidylinositol-specific phospholipase C, which partially cleaved GPI-anchored proteins from the cell surface.
1(0,0,0,1) Details