| Name | integrin |
|---|---|
| Synonyms | Alpha 11 precursor; HsT18964; ITGA11; Integrin; Integrin alpha 11; Integrin alpha 11 precursor; MSTP018; HsT18964s… |
| Name | mercuric chloride |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 11168634 | Roos A, Neeft M, Engelen L, Schilder-Tol EJ, Kunzendorf U, Weening JJ, Aten J: The immune dysregulatory compound mercuric chloride induces integrin-mediated T-lymphocyte adhesion. Immunology. 2001 Jan;102(1):31-8. |
35(0,1,1,5) | Details |
| 8051427 | Molina A, Sanchez-Madrid F, Bricio T, Martin A, Barat A, Alvarez V, Mampaso F: Prevention of mercuric chloride-induced nephritis in the brown Norway rat by treatment with antibodies against the alpha 4 integrin. J Immunol. 1994 Sep 1;153(5):2313-20. |
10(0,0,1,5) | Details |
| 9773789 | Escudero E, Nieto M, Martin A, Molina A, Lobb RR, Sanchez-Madrid F, Mampaso F: Differential effects of antibodies to vascular cell adhesion molecule-1 and distinct epitopes of the alpha4 integrin in HgCl2-induced nephritis in Brown Norway rats. J Am Soc Nephrol. 1998 Oct;9(10):1881-91. |
4(0,0,0,4) | Details |
| 17250768 | Escribese MM, Conde E, Martin A, Saenz-Morales D, Sancho D, Perez de Lema G, Lucio-Cazana J, Sanchez-Madrid F, Garcia-Bermejo ML, Mampaso FM: Therapeutic effect of (at-RA) on an autoimmune nephritis experimental model: role of the VLA-4 integrin. BMC Nephrol. 2007 Jan 24;8:3. BACKGROUND: Mercuric chloride (HgCl2) induces an autoimmune nephritis in the Brown Norway (BN) rats characterized by anti-glomerular basement membrane antibodies (anti-GBM Ab) deposition, proteinuria and a severe interstitial nephritis, all evident at day 13 of the disease. |
4(0,0,0,4) | Details |
| 11169206 | Worth RG, Esper RM, Warra NS, Kindzelskii AL, Rosenspire AL, Todd RF 3rd, Petty HR: Mercury inhibition of neutrophil activity: evidence of aberrant cellular signalling and incoherent cellular metabolism. Scand J Immunol. 2001 Jan;53(1):49-55. We recently reported that the NAD (P) H oscillation frequency is affected by cell migration and activation, which can in turn be regulated by integrin-mediated signalling. |
2(0,0,0,2) | Details |
| 17977980 | Escribese MM, Conde E, Saenz-Morales D, Hordijk PL, Garcia-Bermejo ML: Mononuclear cell extravasation in an inflammatory response is abrogated by through inhibiting the acquisition of an appropriate migratory phenotype. J Pharmacol Exp Ther. 2008 Feb;324(2):454-62. Epub 2007 Oct 31. Our laboratory has previously characterized the inflammatory response developed in the experimental model of mercuric chloride (HgCl (2))-induced nephritis in Brown Norway rats as an acute inflammatory response dependent on very late antigen (VLA)-4. In fact, at-RA inhibits the actin polymerization required for cell morphology changes, and it alters the distribution of F-actin and VLA-4 integrin in focal contacts, essential for cell adhesion. |
1(0,0,0,1) | Details |