Protein Information

Name hemoglobin (protein family or complex)
Synonyms Hemoglobin; Hemoglobins

Compound Information

Name malathion
CAS diethyl 2-[(dimethoxyphosphinothioyl)thio]butanedioate

Reference List

PubMed Abstract RScore(About this table)
1781938 Neskovic NK, Karan VZ, Vitorovic SL, Vojinovic VD: Toxic effects of bound malathion residues in rats. Biomed Environ Sci. 1991 Dec;4(4):423-32.

Hematological data showed changes only in hemoglobin concentration in males (both dose levels).
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18722991 Elsheikha HM, Hussein HS, Rahbar MH: Clinico-pathological effects of Schistosoma mansoni infection associated with simultaneous exposure to malathion in Swiss outbred albino mice. Acta Trop. 2008 Oct;108(1):11-9. Epub 2008 Aug 3.

Alterations observed in infected, exposed mice included (i) higher mortality rate; (ii) severe pathologies in liver and spleen; (iii) increased serum level of bilirubin and alanine aminotransferase/aspartate aminotransferase (ALT/AST) enzymes; (iv) decreased serum level of albumin and total proteins; and (v) decreased red blood cell count (RBC), lymphocytes, leucocytic count, and hemoglobin content.
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20183077 Kundu CR, Roychoudhury S: Malathion-induced sublethal toxicity on the hematology of cricket frog (Fejervarya limnocharis). J Environ Sci Health B. 2009 Sep;44(7):673-80.

Significant decreases (P < 0.01) of hemoglobin and packed cell volume were also observed from 48 hrs to 240 hrs.
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6832123 Mishra J, Srivastava AK: Malathion induced hematological and biochemical changes in the Indian catfish Heteropneustes fossilis. Environ Res. 1983 Apr;30(2):393-8.

Fish developed erythropenia and leukopenia; lowered hematocrit and hemoglobin content and hypercoagulability of blood were also observed.
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