| Name | SRBC |
|---|---|
| Synonyms | CD2; SRBC; CD2 molecule; Erythrocyte receptor; HUMCD2A; LFA 2; LFA 3 receptor; LFA2… |
| Name | malathion |
|---|---|
| CAS | diethyl 2-[(dimethoxyphosphinothioyl)thio]butanedioate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8789791 | Rodgers K, St Amand K, Xiong S: Effects of malathion on humoral immunity and macrophage function in mast cell-deficient mice. Fundam Appl Toxicol. 1996 Jun;31(2):252-8. The hypothesis that mast cells contribute to the observed alterations in humoral immunity and macrophage function was determined by examination of the effects of acute administration of malathion to mast cell-deficient mice on macrophage function and the generation of a humoral immune response to SRBC. |
112(1,2,2,2) | Details |
| 2767956 | Rodgers KE, Haviland DL, Ware CF: Protection from O,O,S-trimethyl phosphorothioate-induced immune suppression. Immunopharmacology. 1989 May-Jun;17(3):131-40. Acute administration of nontoxic doses of an impurity in technical malathion, O,O,S-trimethyl phosphorothioate (OOS-TMP), was able to block the in vitro generation of cytotoxic T lymphocytes (CTL) to alloantigen and antibody-secreting cells (Ab) to sheep red blood cells (SRBC). |
82(1,1,1,2) | Details |
| 9754060 | Banerjee BD, Pasha ST, Hussain QZ, Koner BC, Ray A: A comparative evaluation of immunotoxicity of malathion after subchronic exposure in experimental animals. Indian J Exp Biol. 1998 Mar;36(3):273-82. The effects of sub-chronic doses of malathion exposure on humoral and cell-mediated immune (CMI) responses were studied in male albino mice, rats and rabbits using sheep red blood cells (SRBC), tetanus toxoid and ovalbumin as antigens. |
81(1,1,1,1) | Details |
| 3488742 | Koizumi A, Hasegawa L, Thomas IK, Imamura T: Effect of induction of T-cell-dependent antibody with sheep red blood cells on P-450-dependent and -independent xenobiotic metabolizing enzymes. Biochem Pharmacol. 1986 Aug 15;35(16):2743-8. The effect of an antigenic challenge with sheep red blood cells (SRBC) on the activities of cytochrome P-450-dependent and -independent xenobiotic metabolizing enzymes and on lipid peroxidation in the liver was investigated. Similarly, the difference due to the strain and the H-2 locus was detected in the activities of P-450-independent enzymes such as malathion and diethyl carboxylesterases, glutathione S-transferase, and epoxide hydrolases in microsomal and cytosolic fractions. |
3(0,0,0,3) | Details |
| 1512071 | Flipo D, Bernier J, Girard D, Krzystyniak K, Fournier M: Combined effects of selected insecticides on humoral immune response in mice. Int J Immunopharmacol. 1992 Jul;14(5):747-52. Three insecticides of different chemical classes: organochlorine; dieldrin, organophosphate; malathion, and carbofuran, previously evaluated for their immunotoxic potential, were selected for studies of combined acute exposure in C57B1/6 inbred mice. The humoral response to sheep red blood cells (SRBC) and the functional activities of peritoneal macrophages, such as phagocytosis of fluorescent beads and presentation of a single protein antigen, avidin, were examined after in vivo exposure of mice to different combinations of the selected pesticides and compared with the vehicle controls. |
3(0,0,0,3) | Details |
| 2918686 | Relford RL, Ainsworth AJ, Harkness JE: Effects of a commercial malathion dip preparation on the cellular and humoral immune response of BALB/c mice. Lab Anim Sci. 1989 Jan;39(1):56-9. The cellular immune response was evaluated by in vitro exposure of lymphocytes to mitogens, and the humoral immune response was assessed by using an enzyme-linked immunosorbent assay (ELISA) to quantify antibody production against sheep red blood cells (SRBC). |
1(0,0,0,1) | Details |
| 3877352 | Rodgers KE, Imamura T, Devens BH: Effects of subchronic treatment with O,O,S-trimethyl phosphorothioate on cellular and humoral immune response systems. Toxicol Appl Pharmacol. 1985 Nov;81(2):310-8. The effect of a 14-day treatment with low doses of O,O,S-Trimethyl phosphorothioate (OOS-TMP), an impurity in technical malathion, on the generation of cell-mediated and humoral immune responses was examined in female C57B1/6 mice. At a dose of 0.5 mg/kg/day OOS-TMP, the generation of antibody-secreting cells to sheep red blood cells (SRBC), the production of interleukin 2 (IL-2), and proliferative responses to the mitogens concanavalin A (Con A) and lipopolysaccharide (LPS) were elevated. |
1(0,0,0,1) | Details |