| Name | CBF1 |
|---|---|
| Synonyms | C promoter binding factor 1; CBF 1; CBF1; H 2K binding factor 2; IGKJRB; IGKJRB 1; IGKJRB1; Immunoglobulin kappa J region recombination signal binding protien 1… |
| Name | thiabendazole |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 2185892 | Cai M, Davis RW: Yeast centromere binding protein CBF1, of the helix-loop-helix protein family, is required for chromosome stability and prototrophy. Cell. 1990 May 4;61(3):437-46. Disruption of the CBF1 gene caused a decrease in the growth rate, an increase in the rate of chromosome loss/nondisjunction, and hypersensitivity to the antimitotic drug thiabendazole. |
10(0,0,1,5) | Details |
| 8243994 | Foreman PK, Davis RW: Point mutations that separate the role of Saccharomyces cerevisiae centromere binding factor 1 in chromosome segregation from its role in transcriptional activation. Genetics. 1993 Oct;135(2):287-96. Deletion of the gene encoding Cbf1p results in an increased frequency of chromosome loss, hypersensitivity to low levels of microtubule disrupting drugs (such as thiabendazole and benomyl) and auxotrophy. By polymerase chain reaction-based random mutagenesis of the CBF1 gene we have obtained a number of mutant alleles that make full-length protein with impaired function. |
1(0,0,0,1) | Details |