Protein Information

Name transducin
Synonyms G protein alpha transducing 1; GBT 1; GBT1; GNAT 1; GNAT1; GNATR; Guanine nucleotide binding protein G(T) alpha 1 subunit; Guanine nucleotide binding protein alpha transducing activity polypeptide 1…

Compound Information

Name thiabendazole
CAS

Reference List

PubMed Abstract RScore(About this table)
16249472 Peterson JJ, Orisme W, Fellows J, McDowell JH, Shelamer CL, Dugger DR, Smith WC: A role for cytoskeletal elements in the light-driven translocation of proteins in rod photoreceptors. Invest Ophthalmol Vis Sci. 2005 Nov;46(11):3988-98.

Perturbation of the microtubule cytoskeleton with thiabendazole slowed the translocation of both arrestin and transducin, but only in moving from the outer to the inner segments.
11(0,0,1,6) Details
18623243 Reidel B, Goldmann T, Giessl A, Wolfrum U: The translocation of signaling molecules in dark adapting mammalian rod photoreceptor cells is dependent on the cytoskeleton. Cell Motil Cytoskeleton. 2008 Oct;65(10):785-800.


In vertebrate rod photoreceptor cells, arrestin and the visual G-protein transducin move between the inner segment and outer segment in response to changes in light.
4(0,0,0,4) Details