Protein Information

Name PF4
Synonyms CXCL 4; CXCL4; Iroplact; Oncostatin A; PF 4; PF4; Platelet factor 4; Platelet factor 4 precursor…

Compound Information

Name thiabendazole
CAS

Reference List

PubMed Abstract RScore(About this table)
504797 Sangster NC, Whitlock HV, Russ IG, Gunawan M, Griffin DL, Kelly JD: Trichostrongylus colubriformis and Ostertagia circumcincta resistant to levamisole, morantel tartrate and thiabendazole: occurrence of field strains. Res Vet Sci. 1979 Jul;27(1):106-10.

Mean worm count reductions for adult T colubriformis (PF4) for therapeutic doses of morantel tartrate, thiabendazole and levamisole in crossbreds were 45.7 per cent, 97.3 per cent and zero respectively, and for Merinos 80.7 per cent, 88.3 per cent and 92.0 per cent respectively.
7(0,0,1,2) Details
7255902 Kelly JD, Sangster NC, Porter CJ, Martin IC, Gunawan M: Use of guniea pigs to assay anthelmintic resistance in ovine isolates of Trichostrongylus colubriformis. Res Vet Sci. 1981 Mar;30(2):131-7.

The PF4 strain was resistant to both thiabendazole and levamisole which had relative potencies of 0.168 and 0.255 respectively.
7(0,0,1,2) Details
7455350 Sangster NC, Kelly JD, Whitlock HV, Gunawan M, Porter CJ: Trichostrongylus colubriformis and Ostertagia sp resistant to levamisole, morantel tartrate and thiabendazole: infectivity, pathogenicity and drug efficacy in two breeds of sheep. Res Vet Sci. 1980 Jul;29(1):26-30.

Merino and Border Leicester cross Merino sheep, nine months old, were infected with 10,000 third stage larvae of both Trichostrongylus colubriformis (PF4) and Ostertagia circumcincta/O trifurcata (PF5), known to have varying degrees of resistance to levamisole, morantel tartrate and thiabendazole.
6(0,0,1,1) Details
7455351 Whitlock HV, Sangster NC, Gunawan M, Porter CJ, Kelly JD: Trichostrongylus colubriformis and Ostertagia sp resistant to levamisole, morantel tartrate and thiabendazole: isolation into pure strain and anthelmintic titration. Res Vet Sci. 1980 Jul;29(1):31-5.

Strains of Trichostrongylus colubriformis (designated PF4) and Ostertagia sp (O circumcincta/O trifurcata, designated PF5), with varying degrees of resistance to levamisole, morantel tartrate and thiabendazole were isolated into pure culture.
6(0,0,1,1) Details