Protein Information

Name malate dehydrogenase
Synonyms ME3; Malate dehydrogenase; NADP ME; Pyruvic malic carboxylase; Malic enzyme 3; Mitochondrial NADP(+) dependent malic enzyme 3; Malic enzyme 3s; Mitochondrial NADP(+) dependent malic enzyme 3s

Compound Information

Name thiabendazole
CAS

Reference List

PubMed Abstract RScore(About this table)
3617430 Tejada P, Sanchez-Moreno M, Monteoliva M, Gomez-Banqueri H: Inhibition of malate dehydrogenase enzymes by benzimidazole anthelmintics. Vet Parasitol. 1987 May;24(3-4):269-74.

Determinations were made of the inhibitory activities of four benzimidazole anthelmintics (Albendazole, Parbendazole, Mebendazole and Thiabendazole) on purified extracts of cytoplasmic and mitochondrial malate dehydrogenase obtained from Ascaris suum, Fasciola hepatica and Moniezia expansa.
32(0,1,1,2) Details
3777528 Sharma RK, Singh K, Saxena R, Saxena KK: Effect of some anthelmintics on malate dehydrogenase activity and mortality in two avian nematodes Ascaridia galli and Heterakis gallinae. Angew Parasitol. 1986 Aug;27(3):175-80.

3(0,0,0,3) Details
2795385 Sarwal S, Sanyal SN, Khera S: In vitro effect of benzimidazole drugs on the enzymes of lipid metabolism in Trichuris globulosa. J Parasitol. 1989 Oct;75(5):808-10.

The effects of 2 benzimidazole drugs, fenbendazole and thiabendazole, on the enzymes of lipid metabolism of an intestinal nematode parasite, Trichuris globulosa, have been studied.
Inhibition is competitive in the case of the lipogenic enzymes, malate dehydrogenase and glucose-6-phosphate dehydrogenase; whereas, it is noncompetitive in the case of the lipolytic enzyme, triacylglycerol lipase.
1(0,0,0,1) Details