| Name | glutathione S transferase |
|---|---|
| Synonyms | GST class alpha 2; Gst2; GST class alpha; GST class alpha member 2; GST gamma; GSTA 2; GSTA2; GSTA2 2… |
| Name | thiabendazole |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10431738 | Kerboeuf D, Aycardi J: Unexpected increased thiabendazole tolerance in Haemonchus contortus resistant to anthelmintics by modulation of activity. Parasitol Res. 1999 Aug;85(8-9):713-8. Comparison with changes observed in the cytotoxicity of antitumor or antiprotozoal drugs after modulation suggests that in H. contortus eggs this increased thiabendazole tolerance might depend on different factors, whether associated or not, including the ability of thiabendazole to conjugate with parasitic or analog, the potential toxicity of such conjugates, their cellular distribution, and their role in the expression of glutathione S-transferase activities, and, perhaps, in the regulation of apoptosis. |
81(1,1,1,1) | Details |
| 12408568 | Almli B, Egaas E, Christiansen A, Eklo OM, Lode O, Kallqvist T: Effects of three fungicides alone and in combination on glutathione S-transferase activity (GST) and cytochrome P-450 (CYP 1A1) in the liver and gill of brown trout (Salmo trutta). Mar Environ Res. 2002 Sep-Dec;54(3-5):237-40. Furthermore, continuous exposure to 540 ug/l thiabendazole [2-(thiazol-4'-yl) benzimidazole] in a flow-through system for 4 days significantly increased the gill glutathione S-transferase (GST) activity towards CDNB, whilst hepatic GST and cytochrome P450 (CYP 1A) activities were not increased by the treatment. |
2(0,0,0,2) | Details |
| 11019651 | Toda C, Yasui T, Hashizume K, Nagano H: [Effect of thiabendazole (TBZ) on (GSH) and GSH related enzymes in mice liver]. Yakugaku Zasshi. 2000 Sep;120(9):787-94. Hepatic glutathione S-transferase (GST) activity toward 1,2-dichloro-4-nitrobenzene (DCNB) was significantly elevated 24 h after administrations of TBZ in TBZ and BSO-TBZ groups. |
1(0,0,0,1) | Details |
| 7722883 | Lodovici M, Aiolli S, Monserrat C, Dolara P, Medica A, Di Simplicio P: Effect of a mixture of 15 commonly used pesticides on DNA levels of and xenobiotic metabolizing enzymes in rat liver. J Environ Pathol Toxicol Oncol. 1994;13(3):163-8. The level of 8-OH- in rat liver DNA was measured as an index of oxidative damage after treating rats for 10 days at a dose ranging from 0.75 to 10 mg/kg with a mixture of 15 pesticides (dithiocarbamate, benomyl, thiabendazole, diphenylamine, chlorthalonil, procimidone, methidathion, chlorpyrifos-ethyl, fenarimol, parathion-methyl, chlorpropham, parathion, vinclozolin, chlorfenvinphos, pirimiphos-ethyl) commonly found in foods of central Italy. The administration of the pesticide mixture dose dependently reduced benzo (a) pyrene hydroxylase, N-demethylase activities, peroxidase, glutathione reductase, glutathione-S-transferase and thiol transferase activities in the liver. |
1(0,0,0,1) | Details |
| 2085232 | Kawalek JC, Fetterer RH: Effect of Haemonchus contortus infection on the clearance of antipyrine, sulfobromophthalein, chloramphenicol, and sulfathiazole in lambs. Am J Vet Res. 1990 Dec;51(12):2044-9. Clearance of antipyrine was enhanced by the infection, and thiabendazole treatment did not alter this effect. |
0(0,0,0,0) | Details |