Protein Information

Name beta hexosaminidase
Synonyms Beta N acetylhexosaminidase; Beta hexosaminidase A; Beta hexosaminidase alpha chain; Beta hexosaminidase alpha chain precursor; HEXA; HEXA protein; Hexosaminidase A; Hexosaminidase A preproprotein variant…

Compound Information

Name malathion
CAS diethyl 2-[(dimethoxyphosphinothioyl)thio]butanedioate

Reference List

PubMed Abstract RScore(About this table)
9176556 Xiong S, Rodgers K: Effects of malathion metabolites on degranulation of and mediator release by human and rat basophilic cells. J Toxicol Environ Health. 1997 Jun 6;51(2):159-75.

In the present study, the effects of malathion and malathion derivatives on histamine and beta-hexosaminidase release by RBL-1 cells, rat peritoneal mast cells (RPMC), and human peripheral blood basophils (HPBB) and cutaneous mast calls were examined.
34(0,1,1,4) Details
1387283 Rodgers K, Ellefson D: Mechanism of the modulation of murine peritoneal cell function and mast cell degranulation by low doses of malathion. Agents Actions. 1992 Jan;35(1-2):57-63.

The amount of beta-hexosaminidase, an enzyme released upon immunologic degranulation of mast cells, in the peritoneal lavage fluid of malathion-treated mice was also significantly elevated with 4 hours after malathion administration.
12(0,0,2,2) Details