Protein Information

Name Rho kinase
Synonyms NY REN 35 antigen; P160ROCK; ROCK 1; ROCK1; ROK alpha; ROKa; ROKalpha; Rho associated coiled coil containing protein kinase 1…

Compound Information

Name OCH
CAS 2,3,4,4,5,5,6,6-octachloro-2-cyclohexen-1-one

Reference List

PubMed Abstract RScore(About this table)
16243962 Braverman AS, Doumanian LR, Ruggieri MR Sr: M2 and M3 muscarinic receptor activation of urinary bladder contractile signal transduction. J Pharmacol Exp Ther. 2006 Feb;316(2):875-80. Epub 2005 Oct 21.


Inhibition of rho kinase with (R)-(+)-trans-4-(1-aminoethyl)-N-(4-pyridyl) cyclohexanecarboxamide dihydrochloride (Y-27632) reduces carbachol maximum, carbachol potency, and increases darifenacin affinity.
5(0,0,0,5) Details
16243961 Braverman AS, Tibb AS, Ruggieri MR Sr: M2 and M3 muscarinic receptor activation of urinary bladder contractile signal transduction. J Pharmacol Exp Ther. 2006 Feb;316(2):869-74. Epub 2005 Oct 21.


Inhibition of rho kinase with (R)-(+)-trans-4-(1-aminoethyl)-N-(4-pyridyl) cyclohexanecarboxamide dihydrochloride (Y-27632) reduces carbachol potency and increases darifenacin affinity.
4(0,0,0,4) Details