| Name | Acetylcholinesterase |
|---|---|
| Synonyms | ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant… |
| Name | OCH |
|---|---|
| CAS | 2,3,4,4,5,5,6,6-octachloro-2-cyclohexen-1-one |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17869525 | Yang GY, Oh KA, Park NJ, Jung YS: New oxime reactivators connected with CH2O (CH2) nOCH2 linker and their reactivation potency for organophosphorus agents-inhibited acetylcholinesterase. Bioorg Med Chem. 2007 Dec 15;15(24):7704-10. Epub 2007 Sep 1. New bis-pyridinium oxime reactivators 6 with CH (2) O (CH (2))(2) OCH (2) and CH (2) O (CH (2))(4) OCH (2) linkers between the two pyridinium rings were designed and synthesized. |
3(0,0,0,3) | Details |
| 18666002 | Ghadimi S, Valmoozi AA, Pourayoubi M, Samani KA: Structure-activity study of phosphoramido acid esters as acetylcholinesterase inhibitors. J Enzyme Inhib Med Chem. 2008 Aug;23(4):556-61. Phosphoramido acid esters (CH (3))(2) NP (O) X (p-OC (6) H (4)-CH (3)) (containing P-Cl (1), P-O (2), P-F (3), P-CN (5), and P-N (4,6) bonds, X for 2, 4 and 6 is OCH (3), (C (2) H (5))(2) N and morpholin) have been synthesized to investigate the structure-activity study of AChE enzyme inhibition, through the parameters logP, delta (31) P and IC (50). |
83(1,1,1,3) | Details |
| 15911280 | Kim TH, Kuca K, Jun D, Jung YS: Design and synthesis of new bis-pyridinium oxime reactivators for acetylcholinesterase inhibited by organophosphorous nerve agents. Bioorg Med Chem Lett. 2005 Jun 2;15(11):2914-7. Epub 2005 Apr 21. New bis-pyridinium oxime reactivators connected with a CH (2) CH (2) OCH (2) CH (2) linker between two pyridinium rings were designed and synthesized. |
2(0,0,0,2) | Details |