Protein Information

Name NMDA receptors (protein family or complex)
Synonyms Glutamate [NMDA] receptor; Glutamate [NMDA] receptors; N methyl D aspartate receptor; N methyl D aspartate receptors; NMDA receptor; NMDA receptors

Compound Information

Name OCH
CAS 2,3,4,4,5,5,6,6-octachloro-2-cyclohexen-1-one

Reference List

PubMed Abstract RScore(About this table)
15232837 Lokk J: [Memantine can relieve certain symptoms in Parkinson disease. Lakartidningen. 2004 Jun 3;101(23):2003-6.


One of these is targeting the dysfunctioning glutamatergic neurotransmitter system through the NMDA-receptors.
3(0,0,0,3) Details
10688599 Llansola M, Monfort P, Felipo V: Inhibitors of phospholipase C prevent glutamate neurotoxicity in primary cultures of cerebellar neurons. J Pharmacol Exp Ther. 2000 Mar;292(3):870-6.


The results reported indicate that glutamate neurotoxicity would be mediated by activation of NMDA receptors, leading to activation of nitric-oxide synthase and increased formation of nitric oxide, which results in increased activity of phospholipase C.
1(0,0,0,1) Details