Protein Information

Name apoprotein
Synonyms AD2; APOE; Apo E; Apolipoprotein E; Apolipoprotein E precursor; apoprotein; Apo Es; Apolipoprotein Es…

Compound Information

Name mepanipyrim
CAS

Reference List

PubMed Abstract RScore(About this table)
9882586 Terada M, Mizuhashi F, Murata K, Tomita T: Mepanipyrim, a new fungicide, inhibits intracellular transport of very low density lipoprotein in rat hepatocytes. Toxicol Appl Pharmacol. 1999 Jan 1;154(1):1-11.

The inhibition of the transport of hepatic VLDL appears to result from qualitative changes in VLDL such as alteration of the apoprotein composition and/or insufficient lipidation of VLDL.
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9779416 Terada M, Mizuhashi F, Tomita T, Murata K: Effects of mepanipyrim on lipid metabolism in rats. J Toxicol Sci. 1998 Aug;23(3):235-41.

Because hepatic TG is secreted into the blood by forming VLDL, which consists of TG, TC, PL, and apoprotein, the decrease in serum TG would be mainly ascribable to that in serum VLDL.
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