| Name | CYP2D6 |
|---|---|
| Synonyms | CPD 6; Xenobiotic monooxygenase; Microsomal monooxygenase; Flavoprotein linked monooxygenase; CPD6; CYP2D; CYP2D variant; CYP2D6… |
| Name | MAA |
|---|---|
| CAS | methylarsonic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17035601 | Mayer RT, Dolence EK, Mayer GE: A real-time fluorescence assay for measuring N-dealkylation. . Drug Metab Dispos. 2007 Jan;35(1):103-9. Epub 2006 Oct 11. Tests using expressed CYP1A1, 1A2, 3A4, 3A5, 1B1, 2C9, 2C19, and 2D6 indicated that N-dealkylase activity is specific for CYP1A1 and CYP2D6. |
5(0,0,0,5) | Details |
| 9247840 | Bacracheva N, Tyutyulkova N, Drenska A, Gorantcheva J, Schinzel S, Scholl T, Stoinov A, Tchakarski I, Tentcheva J, Vlahov V: Effect of cimetidine on the pharmacokinetics of the metabolites of metamizol. Int J Clin Pharmacol Ther. 1997 Jul;35(7):275-81. The patients were phenotyped for CYP2D6 and acetylation polymorphism. |
1(0,0,0,1) | Details |
| 8999440 | Lautenschlager MT, Viktor S, Muller UA, Hoffmann A: [Comparison of serum concentrations of 4-methylaminoantipyrine, sulfamethazine and debrisoquin following oral administration of these substances as a cocktail in type II diabetics before and after insulin therapy]. Pharmazie. 1996 Oct;51(10):750-3. A cocktail of 4 substances /CYP1A/CYP1A2, metamizol/CYP2B, debrisoquin/CYP2D6 and sulfamethazine/N-acetyltransferase) was administered to 15 maturity-onset diabetics before and 6 months after insulin therapy (IT) to examine changes in hepatic biotransformation capacity in humans under pathological conditions. |
1(0,0,0,1) | Details |