| Name | HLA DR |
|---|---|
| Synonyms | Cell surface glycoprotein; MHC class I antigen; MHC class II antigen; DR5; Leucocyte antigen B; DR 5; DRB 1; DRB1… |
| Name | MAA |
|---|---|
| CAS | methylarsonic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9924695 | Coral S, Sigalotti L, Gasparollo A, Cattarossi I, Visintin A, Cattelan A, Altomonte M, Maio M: Prolonged upregulation of the expression of HLA class I antigens and costimulatory molecules on melanoma cells treated with 5-aza-2'- (5-AZA-CdR). J Immunother. 1999 Jan;22(1):16-24. The immunogenic potential of melanoma cells and their recognition by the host's cytotoxic cells depends on the presence and on the level of expression of human leukocyte antigen (HLA) class I antigens, costimulatory molecules and melanoma-associated antigens (MAA), on neoplastic cells. |
1(0,0,0,1) | Details |
| 2302716 | Rosenberg CD, Ferrone S, Hamby CV, Mancino V, Graf LH Jr: Interspecific DNA-mediated transfer and amplification of a gene specifying a Mr 100,000 human melanoma-associated cell surface glycoprotein. Cancer Res. 1990 Mar 1;50(5):1559-65. Primary, secondary, and tertiary B78H1 transfectants expressing the Mr 100,000 MAA gene were generated by treatment with coprecipitated DNA from Mr 100,000 MAA+ human or transfectant mouse cells and they were detected by an indirect RBC rosetting assay. |
1(0,0,0,1) | Details |
| 8941875 | Player MA, Barracchini KC, Simonis TB, Rivoltini L, Arienti F, Castelli C, Mazzocchi A, Belli F, Parmiani G, Marincola FM: Differences in frequency distribution of HLA-A2 subtypes between North American and Italian white melanoma patients: relevance for epitope specific vaccination protocols. J Immunother Emphasis Tumor Immunol. 1996 Sep;19(5):357-63. Cytotoxic T lymphocytes (CTL) associated in vivo with tumor regression recognize the product of nonmutated genes expressed by most melanoma cells as peptides bound to human leukocyte antigen (HLA) molecules. |
1(0,0,0,1) | Details |
| 1934567 | Imai R, Miura J, Takamori K, Ogawa H: Increased HLA-DR+ T-lymphocyte population in peripheral blood of alopecia areata. Clin Exp Dermatol. 1991 May;16(3):176-80. Fifty-eight patients with AA were classified into one of three types: those with inactive single AA (type 1) lesions, active multiple alopecia areata (MAA) lesions and active alopecia totalis (AT) (type 2) and chronic alopecia universalis (AU) (type 3). |
2(0,0,0,2) | Details |
| 3889169 | Ernstoff MS, Duray P, Stenn K, Kirkwood JM: Antigenic phenotype of pigment cell lesions: a study of melanoma, its precursor lesions and heterogeneity in metastatic melanoma. J Invest Dermatol. 1985 May;84(5):430-2. We have demonstrated expression of HLA-DR, beta 2-microglobulin, and 2 melanoma-associated antigens (MAA) in a range of benign and malignant lesion, and have confirmed the close association of HLA-DR and MAA on malignant lesions. |
6(0,0,1,1) | Details |
| 10432284 | Wang Z, Marincola FM, Rivoltini L, Parmiani G, Ferrone S: Selective histocompatibility leukocyte antigen (HLA)-A2 loss caused by aberrant pre-mRNA splicing in 624MEL28 melanoma cells. J Exp Med. 1999 Jul 19;190(2):205-15. |
2(0,0,0,2) | Details |
| 11092052 | Abken H, Hombach A, Heuser C, Reinhold U: A novel strategy in the elimination of disseminated melanoma cells: chimeric receptors endow T cells with tumor specificity. Recent Results Cancer Res. 2001;158:249-64. Cytotoxic T cells grafted with the chimeric anti-HMW-MAA scFv-gamma signaling receptor specifically lyse HMW-MAA-positive melanoma cells in a human leukocyte antigen class I-independent fashion. |
1(0,0,0,1) | Details |
| 8419461 | Kameda Y, Hirota C: Production of a monoclonal antibody against cell-surface glycoprotein of guinea pig adrenocortical cells. J Histochem Cytochem. 1993 Feb;41(2):235-43. |
1(0,0,0,1) | Details |
| 15373771 | Mittelman A, Tiwari R, Lucchese G, Willers J, Dummer R, Kanduc D: Identification of monoclonal anti-HMW-MAA antibody linear peptide epitope by proteomic database mining. J Invest Dermatol. 2004 Oct;123(4):670-5. The present result has been obtained by applying as driving criteria the analysis of the peptide affinity to MHC class II molecules and the non-self discrimination concept. |
1(0,0,0,1) | Details |
| 19386352 | Meije CB, Swart GW, Lepoole C, Das PK, Van den Oord JJ: Antigenic profiles of individual-matched pairs of primary and melanoma metastases. Hum Pathol. 2009 Oct;40(10):1399-407. Epub 2009 Apr 22. A unique collection of individual-matched pairs of primary and melanoma metastases were studied immunohistochemically with a panel of 6 monoclonal antibodies directed to gp-100, pigmentation-associated antigen, tyrosinase-related protein, human leukocyte antigen DR, MAA-1, and MAA-2 (high molecular weight melanoma-associated antigens). |
1(0,0,0,1) | Details |