| Name | progesterone receptor |
|---|---|
| Synonyms | NR3C3; PGR; PR; Progesterone receptor; Progesterone receptors |
| Name | MAMA |
|---|---|
| CAS | ammonium hydrogen methylarsonate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 7918738 | O'Neil JP, Carlson KE, Anderson CJ, Welch MJ, Katzenellenbogen JA: radiopharmaceuticals labeled with technetium and rhenium: synthesis, binding affinity, and in vivo distribution of a new N2S2-metal conjugate. Bioconjug Chem. 1994 May-Jun;5(3):182-93. In competitive binding assays, the Re- and 99Tc-MAMA'- conjugates bind to the progesterone receptor with affinities greater than that of itself, and in a direct binding assay, the equilibrium dissociation constant (Kd) of the 99mTc-MAMA' conjugate was 0.97 nM. |
82(1,1,1,2) | Details |
| 12556966 | Schneider J, Pollan M, Tejerina A, Sanchez J, Lucas AR: Accumulation of uPA-PAI-1 complexes inside the tumour cells is associated with axillary nodal invasion in progesterone-receptor-positive early breast cancer. Br J Cancer. 2003 Jan 13;88(1):96-101. |
3(0,0,0,3) | Details |
| 12793902 | Nunez-Villar MJ, Martinez-Arribas F, Pollan M, Lucas AR, Sanchez J, Tejerina A, Schneider J: Elevated mammaglobin (h-MAM) expression in breast cancer is associated with clinical and biological features defining a less aggressive tumour phenotype. Breast Cancer Res. 2003;5(3):R65-70. Epub 2003 Mar 6. RESULTS: In the univariate analysis, high h-MAM expression (above the median for the whole group) correlated significantly (P < 0.05) with oestrogen and progesterone receptor expression, diploid DNA content, low Ki67 labelling index, low nuclear grade and almost significantly (P = 0.058) with the absence of axillary nodal invasion in the mastectomy specimen. |
2(0,0,0,2) | Details |
| 16475699 | Martinez-Arribas F, Martin-Garabato E, Lafuente P, Tejerina A, Lucas R, Sanchez J, Schneider J: Proliferation measurement in breast cancer by two different methods. Anticancer Res. 2006 Jan-Feb;26(1A):199-202. Furthermore, hormone receptor (estrogen receptor, ER; progesterone receptor, PR), c-erb-B2 and p53 expressions were studied using the same method. |
1(0,0,0,1) | Details |
| 11305953 | Schneider J, Gonzalez-Roces S, Pollan M, Lucas R, Tejerina A, Martin M, Alba A: Expression of LRP and MDR1 in locally advanced breast cancer predicts axillary node invasion at the time of rescue mastectomy after induction chemotherapy. Breast Cancer Res. 2001;3(3):183-91. Epub 2001 Feb 1. Immunohistochemistry for detecting the expression of c-erb-B2, p53, Ki67, estrogen receptor and progesterone receptor are routinely performed in our laboratory in every case, and the results obtained were included in the study. |
1(0,0,0,1) | Details |
| 16552754 | Martinez-Arribas F, Agudo D, Pollan M, Gomez-Esquer F, Diaz-Gil G, Lucas R, Schneider J: Positive correlation between the expression of X-chromosome RBM genes (RBMX, RBM3, RBM10) and the proapoptotic Bax gene in human breast cancer. J Cell Biochem. 2006 Apr 15;97(6):1275-82. Markers of hormone dependence and progesterone receptors), proliferation (Ki67 and DNA-ploidy), angiogenesis (VEGF and CD105), as well as oncogene (c-erb-B2), and tumor suppressor gene (p53) expression were also analyzed. |
1(0,0,0,1) | Details |
| 18204202 | Schneider J, Tejerina A, Perea C, Lucas R, Sanchez J: Molecular subgroups of small (pT1) breast carcinomas belonging exclusively to the ductal infiltrating variety. Cancer Genomics Proteomics. 2007 Nov-Dec;4(6):399-402. MATERIALS AND METHODS: This study was restricted to the ductal infiltrating variety only, and to pT1 size using the immunohistochemical markers estrogen receptor (ER), progesterone receptor (PR), HER2 and cytokeratin 5/6. |
1(0,0,0,1) | Details |
| 17352236 | Martinez-Arribas F, Alvarez T, Del Val G, Martin-Garabato E, Nunez-Villar MJ, Lucas R, Sanchez J, Tejerina A, Schneider J: Bcl-2 expression in breast cancer: a comparative study at the mRNA and protein level. Anticancer Res. 2007 Jan-Feb;27(1A):219-22. RESULTS: Any degree of immunohistochemical staining correlated significantly and inversely with c-erb-B2 expression (p = 0.0008), nuclear grade 3 (p = 0.0015), a Ki-67 labeling index > 10% (p = 0.02) and tumor size (p = 0.048), and in a direct fashion with (p = 0.0003) and progesterone receptor expression (p = 0.0002). mRNA expression of the Bcl-2 gene showed a significant inverse correlation with c-erb-B2 (p = 0.016) and p53 (p = 0.014) expression, as well as with a nuclear grade 3 (p = 0.006), and a direct correlation with (p = 0.0004) and (p = 0.001) receptor expression, as well as with nodal invasion (p = 0.04). |
1(0,0,0,1) | Details |
| 10567878 | Schneider J, Pollan M, Ruibal A, Jimenez E, Lucas AR, Nunez MI, Sanchez J, Tejerina A: Histologic grade and CD44 are independent predictors of axillary lymph node invasion in early (T1) breast cancer. Tumour Biol. 1999 Nov-Dec;20(6):319-30. Patients and Methods: We reviewed the records of 135 patients with unifocal invasive breast cancers, 2 cm or less in diameter, operated upon at 'Fundacion Tejerina-Centro de Patologia de la Mama', Madrid, Spain, between January 1993 and December 1997. Full clinical and pathological data were available for all of them, together with and progesterone receptor determinations, which had been routinely performed in 134 and 133 cases, respectively. |
1(0,0,0,1) | Details |