Protein Information

Name CFTR
Synonyms ABC35; ABCC 7; ABCC7; ATP binding cassette transporter sub family C member 7; CF; CFTR; CFTR/MRP; MRP 7…

Compound Information

Name sodium arsenite
CAS sodium arsenenite

Reference List

PubMed Abstract RScore(About this table)
20207026 Shaw JR, Bomberger JM, Vanderheide J, Lacasse T, Stanton S, Coutermarsh B, Barnaby R, Stanton BA: Arsenic inhibits SGK1 activation of CFTR Cl (-) channels in the gill of killifish, Fundulus heteroclitus. Aquat Toxicol. 2010 Feb 6.

Since arsenic exposure prevents acclimation to seawater by decreasing CFTR protein levels we tested the hypothesis that arsenic (as sodium arsenite) blocks acclimation to seawater by down regulating SGK1 expression.
38(0,1,1,8) Details