Name | CHOP |
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Synonyms | 75 kDa DNA pairing protein; FUS1; CHOP; FUS; FUS 1; FUS CHOP; FUS/ATF1fusion gene; FUS/CHOP fusion gene… |
Name | sodium arsenite |
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CAS | sodium arsenenite |
PubMed | Abstract | RScore(About this table) | |
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10542372 | Fontanier-Razzaq NC, Hay SM, Rees WD: Upregulation of CHOP-10 (gadd153) expression in the mouse blastocyst as a response to stress. Mol Reprod Dev. 1999 Dec;54(4):326-32. When mouse blastocysts were exposed to the alkylating agent MMS, the metabolic inhibitor sodium arsenite or an inhibitor of protein glycosylation tunicamycin, levels of the CHOP-10 mRNA were increased by two- to threefold relative to the mRNA for beta-actin. |
93(1,1,2,8) | Details |
11145585 | Entingh AJ, Law BK, Moses HL: Induction of the C/EBP homologous protein (CHOP) by amino acid deprivation requires insulin-like growth factor I, phosphatidylinositol 3-kinase, and mammalian target of rapamycin signaling. Endocrinology. 2001 Jan;142(1):221-8. LY294002 and rapamycin are also able to block CHOP induction by peroxide, but do not affect expression induced by sodium arsenite or A23187. |
7(0,0,0,7) | Details |
11319142 | Fontanier-Razzaq N, McEvoy TG, Robinson JJ, Rees WD: DNA damaging agents increase gadd153 (CHOP-10) messenger RNA levels in bovine preimplantation embryos cultured in vitro. Biol Reprod. 2001 May;64(5):1386-91. Treatment of bovine granulosa cell cultures with the DNA-damaging agents, methyl -sulphonate (MMS) or sodium arsenite, induced the expression of an mRNA, which hybridized with the hamster gadd153 cDNA. |
2(0,0,0,2) | Details |
17681577 | Lin AM, Chao PL, Fang SF, Chi CW, Yang CH: Endoplasmic reticulum stress is involved in arsenite-induced oxidative injury in rat brain. Toxicol Appl Pharmacol. 2007 Oct 15;224(2):138-46. Epub 2007 Jul 3. In ER pathway, arsenite increased activating transcription factor-4, X-box binding protein 1, C/EBP homologues protein (CHOP) and cytosolic immunoglobulin binding protein levels. The mechanism underlying sodium arsenite (arsenite)-induced neurotoxicity was investigated in rat brain. |
1(0,0,0,1) | Details |